Correlates of increased risk for alcoholism in young men

Sean O'Connor, Victor Hesselbrock, Tasman Allan

Research output: Contribution to journalArticle

65 Scopus citations


1. 1. Healthy men, aged 21-28, were divided into two groups according to the DSM-III diagnosis of alcoholism in their biological fathers. 2. 2. Evoked potentials from each subject were measured according to a visual odd-ball paradigm designed to elicit large responses in the midline parietal, Pz, lead. 3. 3. Subjects with alcoholic fathers produced significantly smaller amplitudes of the P3 component compared to subjects with non-alcoholic fathers. 4. 4. Reaction time, task difficulty and subject drinking history did not distinguish the groups. 5. 5. Subject's drinking history was not related to P3 amplitude.

Original languageEnglish (US)
Pages (from-to)211-218
Number of pages8
JournalProgress in Neuropsychopharmacology and Biological Psychiatry
Issue number2
StatePublished - 1986
Externally publishedYes


  • ERP
  • P3 amplitude
  • alcoholism
  • drinking history
  • genetic risk

ASJC Scopus subject areas

  • Pharmacology
  • Biological Psychiatry

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