Correlation of Infecting Serovar and Local Inflammation in Genital Chlamydial Infections

Byron E. Batteiger, Wayne Lennington, J. Wilbert, V. Newhall, Barry R. Katz, Howard T. Morrison, Robert B. Jones

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

The relationship between acute inflammation and serovar of Chlamydia trachomatis was evaluated in patients with genital chlamydial infection who attended a sexually transmitted diseases clinic. Polymorphonuclear leukocytes (PMNLS) were enumerated on Gram's-stained smears of endourethral contents in men; cervicitis was scored by visual observation of the endocervix in women. Isolates were serotyped with a monoclonal antibody-based radioimmunoassay. The distribution of serovars in 99 women did not differ in the presence or absence of cervicitis or concurrent gonorrheae. An overall difference (P = .037) was observed when serovar distributions in men with ≤ 3 PMNLs (n = 42), ≥ 10 PMNLs (n = 41), and gonococcal urethritis (n = 42) were compared. Follow-up pairwise comparisons revealed that men with ≤ 3 PMNLs had fewer isolates of serovars F and G than did men with ≥ 10 PMNLs (P < .05). No strong overall association was observed between inflammation and serovar.

Original languageEnglish (US)
Pages (from-to)332-336
Number of pages5
JournalJournal of Infectious Diseases
Volume160
Issue number2
DOIs
StatePublished - Aug 1989

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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    Batteiger, B. E., Lennington, W., Wilbert, J., Newhall, V., Katz, B. R., Morrison, H. T., & Jones, R. B. (1989). Correlation of Infecting Serovar and Local Inflammation in Genital Chlamydial Infections. Journal of Infectious Diseases, 160(2), 332-336. https://doi.org/10.1093/infdis/160.2.332