Correlation of infecting serovar and local inflammation in genital chlamydial infections

Byron Batteiger, W. Lennington, W. J. Newhall, B. P. Katz, Barry Katz, R. B. Jones

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The relationship between acute inflammation and serovar of Chlamydia trachomatis was evaluated in patients with genital chlamydial infection who attended a sexually transmitted diseases clinic. Polymorphonuclear leukocytes (PMNLS) were enumerated on Gram's-stained smears of endourethral contents in men; cervicitis was scored by visual observation of the endocervix in women. Isolates were serotyped with a monoclonal antibody-based radioimmunoassay. The distribution of serovars in 99 women did not differ in the presence or absence of cervicitis or concurrent gonorrheae. An overall difference (P = .037) was observed when serovar distributions in men with ≤ 3 PMNLs (n = 42), ≥ 10 PMNLs (n = 41), and gonococcal urethritis (n = 42) were compared. Follow-up pairwise comparisons revealed that men with ≤ 3 PMNLs had fewer isolates of serovars F and G than did men with ≥ 10 PMNLs (P < .05). No strong overall association was observed between inflammation and serovar.

Original languageEnglish
Pages (from-to)332-336
Number of pages5
JournalJournal of Infectious Diseases
Volume160
Issue number2
StatePublished - 1989

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Inflammation
Uterine Cervicitis
Infection
Urethritis
Gonorrhea
Chlamydia trachomatis
Sexually Transmitted Diseases
Radioimmunoassay
Neutrophils
Monoclonal Antibodies
Observation
Serogroup

ASJC Scopus subject areas

  • Immunology
  • Public Health, Environmental and Occupational Health

Cite this

Correlation of infecting serovar and local inflammation in genital chlamydial infections. / Batteiger, Byron; Lennington, W.; Newhall, W. J.; Katz, B. P.; Katz, Barry; Jones, R. B.

In: Journal of Infectious Diseases, Vol. 160, No. 2, 1989, p. 332-336.

Research output: Contribution to journalArticle

Batteiger, Byron ; Lennington, W. ; Newhall, W. J. ; Katz, B. P. ; Katz, Barry ; Jones, R. B. / Correlation of infecting serovar and local inflammation in genital chlamydial infections. In: Journal of Infectious Diseases. 1989 ; Vol. 160, No. 2. pp. 332-336.
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