Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections

Mark J. Lowe, Mario Dzemidzic, Joseph T. Lurito, Vincent Mathews, Micheal D. Phillips

Research output: Contribution to journalArticle

196 Citations (Scopus)

Abstract

Cross-correlation of low-frequency temporal fluctuations (<0.08 Hz) was used to correlate widely separated anatomic regions during continuous performance of a spatial working memory task. The regions of highest correlation to right-hemisphere dorsolateral prefrontal cortex correspond to the regions of largest baseline signal change in a conventional block-style functional MRI paradigm. Additionally, it is shown that the correlations between elements of the functional network increase during performance of a task that activates the network when compared to a task that does not directly stimulate the functionally connected network. (C) 2000 Academic Press.

Original languageEnglish
Pages (from-to)582-587
Number of pages6
JournalNeuroImage
Volume12
Issue number5
DOIs
StatePublished - 2000

Fingerprint

Task Performance and Analysis
Prefrontal Cortex
Short-Term Memory
Magnetic Resonance Imaging
Spatial Memory

Keywords

  • Dorsolateral prefrontal cortex
  • Functional magnetic resonance imaging
  • Physiologic noise
  • Resting state correlation
  • Working memory

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections. / Lowe, Mark J.; Dzemidzic, Mario; Lurito, Joseph T.; Mathews, Vincent; Phillips, Micheal D.

In: NeuroImage, Vol. 12, No. 5, 2000, p. 582-587.

Research output: Contribution to journalArticle

Lowe, Mark J. ; Dzemidzic, Mario ; Lurito, Joseph T. ; Mathews, Vincent ; Phillips, Micheal D. / Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections. In: NeuroImage. 2000 ; Vol. 12, No. 5. pp. 582-587.
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