Cortical adaptation following partial glossectomy with primary closure: Implications for reconstruction of the oral tongue

Kristine Mosier, Wen Ching Liu, Babak Behin, Christopher Lee, Soly Baredes

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objectives: The considerable variability in functional outcomes for speech and swallowing with different reconstruction techniques following partial glossectomy may reflect the ability of patients to adapt to altered tongue structure. The purpose of this study was to determine mechanisms of cortical adaptation in swallowing to partial glossectomy reconstructed with primary closure. Methods: Four patients treated with partial glossectomy and primary closure underwent functional magnetic resonance imaging at a mean of 6 months after operation, and the data were compared to those from 8 healthy controls. Results: Statistically significant increases in activity occurred predominately in the parietal cortices and the cerebellum. The volume of the resection was most highly correlated with activity in the premotor and parietal cortices and cerebellum. Conclusions: The adaptive changes in the cortex following partial glossectomy with primary closure reflect adaptation to the biomechanics of tongue movement during swallowing, and not altered sensation in the tongue.

Original languageEnglish (US)
Pages (from-to)681-687
Number of pages7
JournalAnnals of Otology, Rhinology and Laryngology
Volume114
Issue number9
DOIs
StatePublished - Sep 2005

Fingerprint

Glossectomy
Tongue
Deglutition
Parietal Lobe
Cerebellum
Aptitude
Motor Cortex
Biomechanical Phenomena
Magnetic Resonance Imaging

Keywords

  • Adaptation
  • Functional magnetic resonance imaging
  • Functional outcome
  • Partial glossectomy
  • Primary closure

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Cortical adaptation following partial glossectomy with primary closure : Implications for reconstruction of the oral tongue. / Mosier, Kristine; Liu, Wen Ching; Behin, Babak; Lee, Christopher; Baredes, Soly.

In: Annals of Otology, Rhinology and Laryngology, Vol. 114, No. 9, 09.2005, p. 681-687.

Research output: Contribution to journalArticle

@article{398d5d1bc0644d40b7b65ec389deff04,
title = "Cortical adaptation following partial glossectomy with primary closure: Implications for reconstruction of the oral tongue",
abstract = "Objectives: The considerable variability in functional outcomes for speech and swallowing with different reconstruction techniques following partial glossectomy may reflect the ability of patients to adapt to altered tongue structure. The purpose of this study was to determine mechanisms of cortical adaptation in swallowing to partial glossectomy reconstructed with primary closure. Methods: Four patients treated with partial glossectomy and primary closure underwent functional magnetic resonance imaging at a mean of 6 months after operation, and the data were compared to those from 8 healthy controls. Results: Statistically significant increases in activity occurred predominately in the parietal cortices and the cerebellum. The volume of the resection was most highly correlated with activity in the premotor and parietal cortices and cerebellum. Conclusions: The adaptive changes in the cortex following partial glossectomy with primary closure reflect adaptation to the biomechanics of tongue movement during swallowing, and not altered sensation in the tongue.",
keywords = "Adaptation, Functional magnetic resonance imaging, Functional outcome, Partial glossectomy, Primary closure",
author = "Kristine Mosier and Liu, {Wen Ching} and Babak Behin and Christopher Lee and Soly Baredes",
year = "2005",
month = "9",
doi = "10.1177/000348940511400905",
language = "English (US)",
volume = "114",
pages = "681--687",
journal = "Annals of Otology, Rhinology and Laryngology",
issn = "0003-4894",
publisher = "Annals Publishing Company",
number = "9",

}

TY - JOUR

T1 - Cortical adaptation following partial glossectomy with primary closure

T2 - Implications for reconstruction of the oral tongue

AU - Mosier, Kristine

AU - Liu, Wen Ching

AU - Behin, Babak

AU - Lee, Christopher

AU - Baredes, Soly

PY - 2005/9

Y1 - 2005/9

N2 - Objectives: The considerable variability in functional outcomes for speech and swallowing with different reconstruction techniques following partial glossectomy may reflect the ability of patients to adapt to altered tongue structure. The purpose of this study was to determine mechanisms of cortical adaptation in swallowing to partial glossectomy reconstructed with primary closure. Methods: Four patients treated with partial glossectomy and primary closure underwent functional magnetic resonance imaging at a mean of 6 months after operation, and the data were compared to those from 8 healthy controls. Results: Statistically significant increases in activity occurred predominately in the parietal cortices and the cerebellum. The volume of the resection was most highly correlated with activity in the premotor and parietal cortices and cerebellum. Conclusions: The adaptive changes in the cortex following partial glossectomy with primary closure reflect adaptation to the biomechanics of tongue movement during swallowing, and not altered sensation in the tongue.

AB - Objectives: The considerable variability in functional outcomes for speech and swallowing with different reconstruction techniques following partial glossectomy may reflect the ability of patients to adapt to altered tongue structure. The purpose of this study was to determine mechanisms of cortical adaptation in swallowing to partial glossectomy reconstructed with primary closure. Methods: Four patients treated with partial glossectomy and primary closure underwent functional magnetic resonance imaging at a mean of 6 months after operation, and the data were compared to those from 8 healthy controls. Results: Statistically significant increases in activity occurred predominately in the parietal cortices and the cerebellum. The volume of the resection was most highly correlated with activity in the premotor and parietal cortices and cerebellum. Conclusions: The adaptive changes in the cortex following partial glossectomy with primary closure reflect adaptation to the biomechanics of tongue movement during swallowing, and not altered sensation in the tongue.

KW - Adaptation

KW - Functional magnetic resonance imaging

KW - Functional outcome

KW - Partial glossectomy

KW - Primary closure

UR - http://www.scopus.com/inward/record.url?scp=25144479849&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=25144479849&partnerID=8YFLogxK

U2 - 10.1177/000348940511400905

DO - 10.1177/000348940511400905

M3 - Article

C2 - 16240930

AN - SCOPUS:25144479849

VL - 114

SP - 681

EP - 687

JO - Annals of Otology, Rhinology and Laryngology

JF - Annals of Otology, Rhinology and Laryngology

SN - 0003-4894

IS - 9

ER -