Cortical resection for epilepsy in children with linear sebaceous nevus syndrome

Cormac O. Maher, Aaron A. Cohen-Gadol, Corey Raffel

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Linear sebaceous nevus syndrome (LSNS) is a rare neurocutaneous syndrome that is associated with seizures and mental retardation. The cortical abnormalities that are associated with this syndrome include focal cortical dysplasia, partial hemimegalencephaly and holohemispheric hemimegalencephaly. Few reports have addressed the utility of cortical resections for epilepsy treatment in the setting of LSNS. We report 3 children with this syndrome who underwent extensive cortical resections and experienced significant improvement in seizure frequency. Our results support the utility of extensive cortical resections for children with this condition.

Original languageEnglish (US)
Pages (from-to)129-135
Number of pages7
JournalPediatric Neurosurgery
Volume39
Issue number3
DOIs
StatePublished - Aug 11 2003
Externally publishedYes

Keywords

  • Epidermal nevus syndrome
  • Epilepsy
  • Linear sebaceous nevus syndrome
  • Neurocutaneous syndromes
  • Seizures

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Clinical Neurology

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