Counteractive effect of antacid suspensions on intrinsic dental erosion

Cecilia P. Turssi, Lídia M.F.F. Vianna, Anderson T. Hara, Flávia L.B. do Amaral, Fabiana M.G. França, Roberta T. Basting

Research output: Contribution to journalArticle

12 Scopus citations


This in vitro study aimed to investigate the anti-erosive effect of antacid suspensions applied to enamel after exposure to hydrochloric acid (HCl). Ninety bovine enamel slabs were embedded, flattened, and polished. Reference areas were created and specimens were divided into six groups. They were exposed to 0.01 M HCl (pH 2) for 2 min, followed by immersion for 1 min in one of the following test suspensions: magnesium hydroxide, aluminum hydroxide, magnesium hydroxide/aluminum hydroxide, sodium alginate/sodium bicarbonate/calcium carbonate, or hydrated magnesium aluminate. Artificial saliva was used as a negative control. Specimens were subjected to a total of five cycles of erosion/antacid treatment. Enamel surface loss was measured (in micrometers) by optical profilometry. In addition, baseline and final surface microhardness (SMH) values of enamel were obtained. It was found that antacid suspensions significantly reduced enamel loss, and that similar protection was afforded by all formulations. No differences were observed between the final enamel SMH values among groups. Antacid suspensions counteracted HCl-induced enamel loss, although they were not effective in reducing enamel softening. Mouth rinsing with antacid suspensions after vomiting can potentially represent a promising strategy to counteract enamel loss caused by erosion.

Original languageEnglish (US)
Pages (from-to)349-352
Number of pages4
JournalEuropean Journal of Oral Sciences
Issue number4
StatePublished - Aug 1 2012


  • Antacid suspensions
  • Enamel
  • Erosion
  • Gastric acid
  • Prevention and control

ASJC Scopus subject areas

  • Dentistry(all)

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  • Cite this

    Turssi, C. P., Vianna, L. M. F. F., Hara, A. T., do Amaral, F. L. B., França, F. M. G., & Basting, R. T. (2012). Counteractive effect of antacid suspensions on intrinsic dental erosion. European Journal of Oral Sciences, 120(4), 349-352.