Cryopreservation of marrow and stromal progenitor cells: Use of long-term liquid culture as a measure of the recovery of renewable hematopoietic and stromal cells

H. S. Boswell, E. O. Niskanen, M. A. Coppola, P. J. Quesenberry

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Long-term liquid culture was used to assess the broad functional integrity of murine bone marrow after cryopreservation. Cryopreserved and thawed marrow contained not only renewable hematopoietic stem cells, but also stromal progenitor cells capable of transferring the hematopoietic microenvironment to liquid culture. Long-term liquid culture may be a superior method of assessing the functional potential of cryopreserved marrow when compared to stem cell assays alone.

Original languageEnglish (US)
Pages (from-to)315-323
Number of pages9
JournalExperimental Hematology
Volume11
Issue number4
StatePublished - Jan 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Hematology
  • Genetics
  • Cell Biology
  • Cancer Research

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