Cryptococcal glucoxylomannan does not exhibit cross-reactivity in the MVista Histoplasma antigen enzyme immunoassay

David Zhuang, Chadi Hage, Magdia De Jesus, Emily Hackett, Michelle Durkin, Thomas E. Davis, Arturo Casadevall, L. Joseph Wheat

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The potential for cross-reaction between Cryptococcus neoformans and Histoplasma capsulatum in antigen assays was evaluated. We tested patient samples, spleens from infected mice, and purified polysaccharides in the MVista Histoplasma antigen enzyme immunoassay and cryptococcal antigen latex agglutination system for cross-reactivity, and none was observed.

Original languageEnglish (US)
Pages (from-to)392-393
Number of pages2
JournalClinical and Vaccine Immunology
Volume15
Issue number2
DOIs
StatePublished - Feb 1 2008

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry
  • Microbiology (medical)

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