Culture characteristics of human granulocyte-macrophage progenitor cells and their regulation in the context of bone marrow transplantation.

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Abstract

Aspects of the granulocyte-macrophage progenitor cell (CFU-GM) assay not previously used in the content of bone marrow transplantation were discussed in terms of the additional information which could be derived. This focused on the characteristics and responsiveness of the progenitor cells to regulatory activities and other agents. In addition, Ia-like antigenic determinants were demonstrated on human "pre-CFU-GM", an assay which can be used to assess what appears to be a more immature progenitor cell.

Original languageEnglish
Pages (from-to)149-158
Number of pages10
JournalExperimental Hematology
Volume7 Suppl 5
StatePublished - 1979
Externally publishedYes

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Granulocyte-Macrophage Progenitor Cells
Bone Marrow Transplantation
Stem Cells
Epitopes

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Genetics
  • Hematology
  • Oncology
  • Transplantation

Cite this

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abstract = "Aspects of the granulocyte-macrophage progenitor cell (CFU-GM) assay not previously used in the content of bone marrow transplantation were discussed in terms of the additional information which could be derived. This focused on the characteristics and responsiveness of the progenitor cells to regulatory activities and other agents. In addition, Ia-like antigenic determinants were demonstrated on human {"}pre-CFU-GM{"}, an assay which can be used to assess what appears to be a more immature progenitor cell.",
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