Current and future biologic markers for disease progression and relapse in testicular germ cell tumors: A review

Timothy A. Masterson, Kevin R. Rice, Stephen D.W. Beck

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Testicular germ cell tumors represent a biologically unique disease process. These tumors are exquisitely sensitive to platinum-based chemotherapy, can be cured with surgical metastasectomy, and are known for the integration of biologic markers to stage and assign risk. Exploring further biologic markers that offer insight into the molecular mechanisms that contribute to disease biology is important. In this review, we attempt to summarize the utility of the current and some future biologic markers for disease monitoring and relapse.

Original languageEnglish (US)
Pages (from-to)261-271
Number of pages11
JournalUrologic Oncology: Seminars and Original Investigations
Volume32
Issue number3
DOIs
StatePublished - Apr 2014

Keywords

  • Angiogenesis
  • Biomarkers
  • Epigenetics
  • Gene profiling
  • Germ cell tumor
  • Serum tumor markers
  • Testicular cancer

ASJC Scopus subject areas

  • Oncology
  • Urology
  • Medicine(all)

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