Current concepts on interstitial lung disease in children

Michelle Howenstine, Howard Eigen

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Pediatric interstitial lung disease comprises a diverse group of rare conditions characterized by an infiltrative process, abnormal gas exchange, and restrictive lung disease. Although the disorder is similar to its adult counterpart, its course is complicated by the continued need for lung growth and differentiation in infants and children. Knowledge about the pathogenesis, prognosis, and treatment of pediatric interstitial lung disease is limited. Investigators are focusing on defining the cellular mediators of the interstitial damage and describing the role of viral infections in and possible genetic predisposition to interstitial lung disease. Clinicians continue to define the various types of interstitial lung disease and to evaluate the roles of bronchoalveolar lavage, radiography, and biopsy in diagnosis. Together, investigators are working toward the development of specific, targeted therapy that will reduce the significant morbidity and mortality seen in pediatric interstitial lung disease.

Original languageEnglish
Pages (from-to)200-204
Number of pages5
JournalCurrent Opinion in Pediatrics
Volume11
Issue number3
DOIs
StatePublished - 1999

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Interstitial Lung Diseases
Pediatrics
Research Personnel
Bronchoalveolar Lavage
Virus Diseases
Genetic Predisposition to Disease
Radiography
Lung Diseases
Gases
Morbidity
Biopsy
Lung
Mortality
Therapeutics
Growth

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Current concepts on interstitial lung disease in children. / Howenstine, Michelle; Eigen, Howard.

In: Current Opinion in Pediatrics, Vol. 11, No. 3, 1999, p. 200-204.

Research output: Contribution to journalArticle

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