Current issues in the management of secondary hyperparathyroidism and bone disease

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Recent research has demonstrated active bone-like remodelling of vascular tissue in dialysis and non dialysis patients. Cross-sectional studies indicate that the presence of vascular calcification is inversely related to bone mass. Theoretically, the relationship implies that maintaining normal bone turnover and mass may help to decrease vascular calcification. In addition, it is now apparent that phosphorus and the Ca × P product need to be kept as close to normal as possible. Thus, the present goal should be a serum phosphorus of 3.5 - 5.5 mg/dL, a Ca × P product of <55 mg/dL, and a PTH of around 150 - 200 pg/mL with the intact assay. Ten years ago, those goals would have been impossible. However, new pharmacologic agents will make their achievement much more realistic.

Original languageEnglish (US)
Pages (from-to)S241-S246
JournalPeritoneal Dialysis International
Volume21
Issue numberSUPPL. 3
DOIs
StatePublished - Jan 1 2001

Keywords

  • Adynamic bone disease
  • Renal osteodystrophy
  • Secondary hyperparathyroidism

ASJC Scopus subject areas

  • Nephrology

Fingerprint Dive into the research topics of 'Current issues in the management of secondary hyperparathyroidism and bone disease'. Together they form a unique fingerprint.

  • Cite this