Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia

Michael G. Wilcox, Thomas J. Howard, Lora A. Plaskon, Joseph L. Unthank, James A. Madura

Research output: Contribution to journalArticle

82 Scopus citations

Abstract

Nonocclusive mesenteric ischemia (NOMI) is a poorly understood condition marked by progressive intestinal ischemia leading to infarction, sepsis, and death in a high proportion of patients. The mortality rate for this intestinal disorder remains high, even when the diagnosis is made early in the disease course. This paper presents a comprehensive review of NOMI with a detailed discussion of its history, pathophysiology, diagnosis, and treatment.

Original languageEnglish (US)
Pages (from-to)709-716
Number of pages8
JournalDigestive diseases and sciences
Volume40
Issue number4
DOIs
StatePublished - Apr 1 1995

Keywords

  • autoregulation
  • enteral feedings
  • intestinal infarction
  • ischemia-reperfusion injury
  • mesenteric ischemia
  • vasoconstriction

ASJC Scopus subject areas

  • Gastroenterology

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