Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia

Michael G. Wilcox, Thomas Howard, Lora A. Plaskon, Joseph L. Unthank, James A. Madura

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Nonocclusive mesenteric ischemia (NOMI) is a poorly understood condition marked by progressive intestinal ischemia leading to infarction, sepsis, and death in a high proportion of patients. The mortality rate for this intestinal disorder remains high, even when the diagnosis is made early in the disease course. This paper presents a comprehensive review of NOMI with a detailed discussion of its history, pathophysiology, diagnosis, and treatment.

Original languageEnglish
Pages (from-to)709-716
Number of pages8
JournalDigestive Diseases and Sciences
Volume40
Issue number4
DOIs
StatePublished - Apr 1995

Fingerprint

Infarction
Sepsis
Ischemia
History
Mortality
Therapeutics
Mesenteric Ischemia

Keywords

  • autoregulation
  • enteral feedings
  • intestinal infarction
  • ischemia-reperfusion injury
  • mesenteric ischemia
  • vasoconstriction

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia. / Wilcox, Michael G.; Howard, Thomas; Plaskon, Lora A.; Unthank, Joseph L.; Madura, James A.

In: Digestive Diseases and Sciences, Vol. 40, No. 4, 04.1995, p. 709-716.

Research output: Contribution to journalArticle

Wilcox, Michael G. ; Howard, Thomas ; Plaskon, Lora A. ; Unthank, Joseph L. ; Madura, James A. / Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia. In: Digestive Diseases and Sciences. 1995 ; Vol. 40, No. 4. pp. 709-716.
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