Current Treatment of Nausea and Vomiting Associated with Gastroparesis: Antiemetics, Prokinetics, Tricyclics

Jeremy Stapleton, John M. Wo

Research output: Contribution to journalReview article

13 Scopus citations

Abstract

Gastroparesis is a symptomatic chronic disorder characterized by delayed gastric emptying without a mechanical obstruction. Gastroparesis is most often associated with diabetes, gastric surgery, and systemic disorders affecting the neuromuscular control of the stomach. However, no underlying etiology can be found in up to 40% of patients, a condition referred to as idiopathic gastroparesis. Due to the numerous potential etiologies and the highly variable clinical manifestations, the management of gastroparesis is particularly challenging. The purpose of this review is to provide an update on the use of antiemetics, prokinetics, and tricyclics for the treatment for nausea and vomiting associated with gastroparesis.

Original languageEnglish (US)
Pages (from-to)57-72
Number of pages16
JournalGastrointestinal Endoscopy Clinics of North America
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Keywords

  • Antiemetics
  • Gastroparesis
  • Nausea
  • Prokinetics
  • Tricyclics
  • Vomiting

ASJC Scopus subject areas

  • Gastroenterology

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