Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography

Brittani Bungart, Yingchun Cao, Tiffany Yang-Tran, Sean Gorsky, L. U. Lan, Darren Roblyer, Michael Koch, Liang Cheng, Timothy Masterson, Ji Xin Cheng

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Current diagnosis of prostate cancer relies on histological analysis of tissue samples acquired by biopsy, which could benefit from real-time identification of suspicious lesions. Photoacoustic tomography has the potential to provide real-time targets for prostate biopsy guidance with chemical selectivity, but light delivered from the rectal cavity has been unable to penetrate to the anterior prostate. To overcome this barrier, a urethral device with cylindrical illumination is developed for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostate-mimicking phantom.

Original languageEnglish (US)
Article number356707
Pages (from-to)1405-1419
Number of pages15
JournalBiomedical Optics Express
Volume10
Issue number3
DOIs
StatePublished - Mar 1 2019

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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    Bungart, B., Cao, Y., Yang-Tran, T., Gorsky, S., Lan, L. U., Roblyer, D., Koch, M., Cheng, L., Masterson, T., & Cheng, J. X. (2019). Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography. Biomedical Optics Express, 10(3), 1405-1419. [356707]. https://doi.org/10.1364/BOE.10.001405