Cytologic diagnosis of malignant mesothelioma, with particular emphasis on the epithelial noncohesive cell type

Jennie Kho-Duffin, Liang Che Tao, Harvey Cramer, Michele J. Catellier, Daniel Irons, Peter Ng

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The effusion cytologies from 21 cases of malignant mesothelioma (MM) (15 pleural, 6 peritoneal) diagnosed at the Indiana University Medical Center during 1990-1997 were reviewed. Using the classification of Tao (Acta Cytol 1979;23:209-213), 13 cases of MM were of the epithelial cohesive cell type and 8 were of the epithelial noncohesive cell type. While the epithelial cohesive cell type has been discussed in the literature, the epithelial noncohesive cell type has not. The cytomorphologic features for both types are presented with particular emphasis on the noncohesive cell type. The differential diagnosis and use of ancillary confirmatory laboratory tests are briefly discussed. Because of its resemblance to florid reactive mesothelial hyperplasia and the general lack of awareness of the existence of the single- cell pattern of mesothelioma, this diagnosis can often be missed.

Original languageEnglish
Pages (from-to)57-62
Number of pages6
JournalDiagnostic Cytopathology
Volume20
Issue number2
DOIs
StatePublished - Feb 1999

Fingerprint

Epithelial Cells
Mesothelioma
Hyperplasia
Cell Biology
Differential Diagnosis
Malignant Mesothelioma

Keywords

  • Cytopathology
  • Mesothelial cells
  • Mesothelioma
  • Serous effusion

ASJC Scopus subject areas

  • Anatomy

Cite this

Cytologic diagnosis of malignant mesothelioma, with particular emphasis on the epithelial noncohesive cell type. / Kho-Duffin, Jennie; Tao, Liang Che; Cramer, Harvey; Catellier, Michele J.; Irons, Daniel; Ng, Peter.

In: Diagnostic Cytopathology, Vol. 20, No. 2, 02.1999, p. 57-62.

Research output: Contribution to journalArticle

Kho-Duffin, Jennie ; Tao, Liang Che ; Cramer, Harvey ; Catellier, Michele J. ; Irons, Daniel ; Ng, Peter. / Cytologic diagnosis of malignant mesothelioma, with particular emphasis on the epithelial noncohesive cell type. In: Diagnostic Cytopathology. 1999 ; Vol. 20, No. 2. pp. 57-62.
@article{6b3f7041f840481d96c99e93aa9d574c,
title = "Cytologic diagnosis of malignant mesothelioma, with particular emphasis on the epithelial noncohesive cell type",
abstract = "The effusion cytologies from 21 cases of malignant mesothelioma (MM) (15 pleural, 6 peritoneal) diagnosed at the Indiana University Medical Center during 1990-1997 were reviewed. Using the classification of Tao (Acta Cytol 1979;23:209-213), 13 cases of MM were of the epithelial cohesive cell type and 8 were of the epithelial noncohesive cell type. While the epithelial cohesive cell type has been discussed in the literature, the epithelial noncohesive cell type has not. The cytomorphologic features for both types are presented with particular emphasis on the noncohesive cell type. The differential diagnosis and use of ancillary confirmatory laboratory tests are briefly discussed. Because of its resemblance to florid reactive mesothelial hyperplasia and the general lack of awareness of the existence of the single- cell pattern of mesothelioma, this diagnosis can often be missed.",
keywords = "Cytopathology, Mesothelial cells, Mesothelioma, Serous effusion",
author = "Jennie Kho-Duffin and Tao, {Liang Che} and Harvey Cramer and Catellier, {Michele J.} and Daniel Irons and Peter Ng",
year = "1999",
month = "2",
doi = "10.1002/(SICI)1097-0339(199902)20:2<57::AID-DC2>3.0.CO;2-M",
language = "English",
volume = "20",
pages = "57--62",
journal = "Diagnostic Cytopathology",
issn = "8755-1039",
publisher = "Wiley-Liss Inc.",
number = "2",

}

TY - JOUR

T1 - Cytologic diagnosis of malignant mesothelioma, with particular emphasis on the epithelial noncohesive cell type

AU - Kho-Duffin, Jennie

AU - Tao, Liang Che

AU - Cramer, Harvey

AU - Catellier, Michele J.

AU - Irons, Daniel

AU - Ng, Peter

PY - 1999/2

Y1 - 1999/2

N2 - The effusion cytologies from 21 cases of malignant mesothelioma (MM) (15 pleural, 6 peritoneal) diagnosed at the Indiana University Medical Center during 1990-1997 were reviewed. Using the classification of Tao (Acta Cytol 1979;23:209-213), 13 cases of MM were of the epithelial cohesive cell type and 8 were of the epithelial noncohesive cell type. While the epithelial cohesive cell type has been discussed in the literature, the epithelial noncohesive cell type has not. The cytomorphologic features for both types are presented with particular emphasis on the noncohesive cell type. The differential diagnosis and use of ancillary confirmatory laboratory tests are briefly discussed. Because of its resemblance to florid reactive mesothelial hyperplasia and the general lack of awareness of the existence of the single- cell pattern of mesothelioma, this diagnosis can often be missed.

AB - The effusion cytologies from 21 cases of malignant mesothelioma (MM) (15 pleural, 6 peritoneal) diagnosed at the Indiana University Medical Center during 1990-1997 were reviewed. Using the classification of Tao (Acta Cytol 1979;23:209-213), 13 cases of MM were of the epithelial cohesive cell type and 8 were of the epithelial noncohesive cell type. While the epithelial cohesive cell type has been discussed in the literature, the epithelial noncohesive cell type has not. The cytomorphologic features for both types are presented with particular emphasis on the noncohesive cell type. The differential diagnosis and use of ancillary confirmatory laboratory tests are briefly discussed. Because of its resemblance to florid reactive mesothelial hyperplasia and the general lack of awareness of the existence of the single- cell pattern of mesothelioma, this diagnosis can often be missed.

KW - Cytopathology

KW - Mesothelial cells

KW - Mesothelioma

KW - Serous effusion

UR - http://www.scopus.com/inward/record.url?scp=0032929654&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032929654&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1097-0339(199902)20:2<57::AID-DC2>3.0.CO;2-M

DO - 10.1002/(SICI)1097-0339(199902)20:2<57::AID-DC2>3.0.CO;2-M

M3 - Article

C2 - 9951597

AN - SCOPUS:0032929654

VL - 20

SP - 57

EP - 62

JO - Diagnostic Cytopathology

JF - Diagnostic Cytopathology

SN - 8755-1039

IS - 2

ER -