Data mining in brain imaging

V. Megalooikonomou, J. Ford, Li Shen, F. Makedon, Andrew Saykin

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Data mining in brain imaging is proving to be an effective methodology for disease prognosis and prevention. This, together with the rapid accumulation of massive heterogeneous data sets, motivates the need for efficient methods that filter, clarify, assess, correlate and cluster brain-related information. Here, we present data mining methods that have been or could be employed in the analysis of brain images. These methods address two types of brain imaging data: structural and functional. We introduce statistical methods that aid the discovery of interesting associations and patterns between brain images and other clinical data. We consider several applications of these methods, such as the analysis of task-activation, lesion-deficit, and structure morphological variability; the development of probabilistic atlases; and tumour analysis. We include examples of applications to real brain data. Several data mining issues, such as that of method validation or verification, are also discussed.

Original languageEnglish (US)
Pages (from-to)359-394
Number of pages36
JournalStatistical Methods in Medical Research
Volume9
Issue number4
StatePublished - 2000
Externally publishedYes

Fingerprint

Data Mining
Neuroimaging
Imaging
Brain
Activation Analysis
Filter Method
Atlases
Atlas
Prognosis
Statistical method
Correlate
Activation
Tumor
Methodology
Neoplasms

ASJC Scopus subject areas

  • Epidemiology
  • Health Information Management
  • Nursing(all)

Cite this

Megalooikonomou, V., Ford, J., Shen, L., Makedon, F., & Saykin, A. (2000). Data mining in brain imaging. Statistical Methods in Medical Research, 9(4), 359-394.

Data mining in brain imaging. / Megalooikonomou, V.; Ford, J.; Shen, Li; Makedon, F.; Saykin, Andrew.

In: Statistical Methods in Medical Research, Vol. 9, No. 4, 2000, p. 359-394.

Research output: Contribution to journalArticle

Megalooikonomou, V, Ford, J, Shen, L, Makedon, F & Saykin, A 2000, 'Data mining in brain imaging', Statistical Methods in Medical Research, vol. 9, no. 4, pp. 359-394.
Megalooikonomou V, Ford J, Shen L, Makedon F, Saykin A. Data mining in brain imaging. Statistical Methods in Medical Research. 2000;9(4):359-394.
Megalooikonomou, V. ; Ford, J. ; Shen, Li ; Makedon, F. ; Saykin, Andrew. / Data mining in brain imaging. In: Statistical Methods in Medical Research. 2000 ; Vol. 9, No. 4. pp. 359-394.
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