Data visualization speeds review of potential adverse drug events in patients on multiple medications

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Patients on multiple medications are at increased risk for adverse drug events. While physicians can reduce this risk by regularly reviewing the side-effect profiles of their patients' medications, this process can be time-consuming. We created a decision support system designed to expedite reviewing potential adverse reactions through information visualization. The system includes a database containing 16,340 unique drug and side-effect pairs, representing 250 common medications. A numeric score is assigned to each pair reflecting the strength of association between drug and effect. Based on these scores, the system generates graphical adverse reaction maps for any user-selected combination of drugs. A study comparing speed and accuracy of retrieving side-effect data using this tool versus UpToDate® demonstrated a 60% reduction in time to complete a query (61 s vs. 155 s, p < 0.0001) with no decrease in accuracy. These findings suggest that information visualization can significantly expedite review of potential adverse drug events.

Original languageEnglish (US)
Pages (from-to)326-331
Number of pages6
JournalJournal of biomedical informatics
Volume43
Issue number2
DOIs
StatePublished - Apr 1 2010

Keywords

  • Adverse drug events
  • Information visualization
  • Polypharmacy
  • Side-effects

ASJC Scopus subject areas

  • Computer Science Applications
  • Health Informatics

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