Defining normal duration for afterdischarges with repetitive nerve stimulation

A pilot study

Cynthia Bodkin, Kathleen D. Kennelly, Kevin B. Boylan, Julia E. Crook, Michael G. Heckman, Devon I. Rubin

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The presence of afterdischarges on repetitive nerve stimulation may be useful to diagnose cramp fasciculation syndrome, however, the presence and normal duration of afterdischarges has not been well-defined in the normal population and individuals with other neuromuscular diseases. The aim of this pilot study was to describe the distribution of afterdischarge durations in normal controls and patients with peripheral neuropathy. The estimated seventy-fifth percentiles of the afterdischarge durations following tibial nerve repetitive nerve stimulation at 2, 5, 10, and 20 Hz were 315, 688, 745, and 928 milliseconds for 18 normal patients, and 143, 31, 323, and 542 milliseconds for 18 peripheral neuropathy patients respectively. Afterdischarge durations were similar in peripheral neuropathy patients and controls. These findings suggest that afterdischarge durations of more than 500 milliseconds are common in normal controls without subjective cramps and patients with peripheral neuropathy, with some durations beyond 1,000 milliseconds. Therefore, the presence of afterdischarges on repetitive nerve stimulation should be interpreted with caution when evaluating patients for hyperexcitable nerve syndromes.

Original languageEnglish (US)
Pages (from-to)45-49
Number of pages5
JournalJournal of Clinical Neurophysiology
Volume26
Issue number1
DOIs
StatePublished - Feb 2009
Externally publishedYes

Fingerprint

Peripheral Nervous System Diseases
Neuromuscular Diseases
Muscle Cramp
Tibial Nerve
Population

Keywords

  • Afterdischarges
  • Cramp fasciculation syndrome
  • Peripheral nerve hyperexcitability
  • Peripheral neuropathy
  • Repetitive nerve stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology
  • Physiology (medical)
  • Medicine(all)

Cite this

Defining normal duration for afterdischarges with repetitive nerve stimulation : A pilot study. / Bodkin, Cynthia; Kennelly, Kathleen D.; Boylan, Kevin B.; Crook, Julia E.; Heckman, Michael G.; Rubin, Devon I.

In: Journal of Clinical Neurophysiology, Vol. 26, No. 1, 02.2009, p. 45-49.

Research output: Contribution to journalArticle

Bodkin, Cynthia ; Kennelly, Kathleen D. ; Boylan, Kevin B. ; Crook, Julia E. ; Heckman, Michael G. ; Rubin, Devon I. / Defining normal duration for afterdischarges with repetitive nerve stimulation : A pilot study. In: Journal of Clinical Neurophysiology. 2009 ; Vol. 26, No. 1. pp. 45-49.
@article{5ff70dc9463a4c848aedda2dcd953696,
title = "Defining normal duration for afterdischarges with repetitive nerve stimulation: A pilot study",
abstract = "The presence of afterdischarges on repetitive nerve stimulation may be useful to diagnose cramp fasciculation syndrome, however, the presence and normal duration of afterdischarges has not been well-defined in the normal population and individuals with other neuromuscular diseases. The aim of this pilot study was to describe the distribution of afterdischarge durations in normal controls and patients with peripheral neuropathy. The estimated seventy-fifth percentiles of the afterdischarge durations following tibial nerve repetitive nerve stimulation at 2, 5, 10, and 20 Hz were 315, 688, 745, and 928 milliseconds for 18 normal patients, and 143, 31, 323, and 542 milliseconds for 18 peripheral neuropathy patients respectively. Afterdischarge durations were similar in peripheral neuropathy patients and controls. These findings suggest that afterdischarge durations of more than 500 milliseconds are common in normal controls without subjective cramps and patients with peripheral neuropathy, with some durations beyond 1,000 milliseconds. Therefore, the presence of afterdischarges on repetitive nerve stimulation should be interpreted with caution when evaluating patients for hyperexcitable nerve syndromes.",
keywords = "Afterdischarges, Cramp fasciculation syndrome, Peripheral nerve hyperexcitability, Peripheral neuropathy, Repetitive nerve stimulation",
author = "Cynthia Bodkin and Kennelly, {Kathleen D.} and Boylan, {Kevin B.} and Crook, {Julia E.} and Heckman, {Michael G.} and Rubin, {Devon I.}",
year = "2009",
month = "2",
doi = "10.1097/WNP.0b013e3181968f00",
language = "English (US)",
volume = "26",
pages = "45--49",
journal = "Journal of Clinical Neurophysiology",
issn = "0736-0258",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Defining normal duration for afterdischarges with repetitive nerve stimulation

T2 - A pilot study

AU - Bodkin, Cynthia

AU - Kennelly, Kathleen D.

AU - Boylan, Kevin B.

AU - Crook, Julia E.

AU - Heckman, Michael G.

AU - Rubin, Devon I.

PY - 2009/2

Y1 - 2009/2

N2 - The presence of afterdischarges on repetitive nerve stimulation may be useful to diagnose cramp fasciculation syndrome, however, the presence and normal duration of afterdischarges has not been well-defined in the normal population and individuals with other neuromuscular diseases. The aim of this pilot study was to describe the distribution of afterdischarge durations in normal controls and patients with peripheral neuropathy. The estimated seventy-fifth percentiles of the afterdischarge durations following tibial nerve repetitive nerve stimulation at 2, 5, 10, and 20 Hz were 315, 688, 745, and 928 milliseconds for 18 normal patients, and 143, 31, 323, and 542 milliseconds for 18 peripheral neuropathy patients respectively. Afterdischarge durations were similar in peripheral neuropathy patients and controls. These findings suggest that afterdischarge durations of more than 500 milliseconds are common in normal controls without subjective cramps and patients with peripheral neuropathy, with some durations beyond 1,000 milliseconds. Therefore, the presence of afterdischarges on repetitive nerve stimulation should be interpreted with caution when evaluating patients for hyperexcitable nerve syndromes.

AB - The presence of afterdischarges on repetitive nerve stimulation may be useful to diagnose cramp fasciculation syndrome, however, the presence and normal duration of afterdischarges has not been well-defined in the normal population and individuals with other neuromuscular diseases. The aim of this pilot study was to describe the distribution of afterdischarge durations in normal controls and patients with peripheral neuropathy. The estimated seventy-fifth percentiles of the afterdischarge durations following tibial nerve repetitive nerve stimulation at 2, 5, 10, and 20 Hz were 315, 688, 745, and 928 milliseconds for 18 normal patients, and 143, 31, 323, and 542 milliseconds for 18 peripheral neuropathy patients respectively. Afterdischarge durations were similar in peripheral neuropathy patients and controls. These findings suggest that afterdischarge durations of more than 500 milliseconds are common in normal controls without subjective cramps and patients with peripheral neuropathy, with some durations beyond 1,000 milliseconds. Therefore, the presence of afterdischarges on repetitive nerve stimulation should be interpreted with caution when evaluating patients for hyperexcitable nerve syndromes.

KW - Afterdischarges

KW - Cramp fasciculation syndrome

KW - Peripheral nerve hyperexcitability

KW - Peripheral neuropathy

KW - Repetitive nerve stimulation

UR - http://www.scopus.com/inward/record.url?scp=65549109794&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65549109794&partnerID=8YFLogxK

U2 - 10.1097/WNP.0b013e3181968f00

DO - 10.1097/WNP.0b013e3181968f00

M3 - Article

VL - 26

SP - 45

EP - 49

JO - Journal of Clinical Neurophysiology

JF - Journal of Clinical Neurophysiology

SN - 0736-0258

IS - 1

ER -