Definitive treatment of vein of Galen aneurysmal malformation with stereotactic radiosurgery: Report of 2 cases

William J. Triffo, J. Daniel Bourland, Daniel E. Couture, Kevin P. Mcmullen, Stephen B. Tatter, Padraig P. Morris

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Vein of Galen aneurysmal malformations (VGAMs) are uncommon congenital malformations arising from fistulous communication with the median vein of the prosencephalon, a primitive precursor of midline cerebral venous structures. Angiographic embolization is the primary modality for treatment given historically poor microsurgical outcomes. Only a few reports of treatment by Gamma Knife radiosurgery (GKRS) exist in the literature, and the results are variable. The authors present 2 cases of VGAM in which GKRS provided definitive treatment with good outcome: one case involving antenatal presentation of a high-output, mural-type VGAM with complex clinical course refractory to multiple embolic procedures, and the other a choroidal-type VGAM presenting with hemorrhage in an adult and without a feasible embolic approach. With discussion of these cases and review of the literature, the authors advocate inclusion of GKRS as a therapeutic option for treatment of these complex lesions.

Original languageEnglish (US)
Pages (from-to)120-125
Number of pages6
JournalJournal of neurosurgery
Volume120
Issue number1
DOIs
StatePublished - Jan 1 2014

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Keywords

  • Arteriovenous malformation
  • Congenital malformation
  • Embolization
  • Gamma Knife radiosurgery
  • Neurosurgery
  • Stereotactic radiosurgery
  • Vascular disorders
  • Vein of Galen malformation

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Triffo, W. J., Bourland, J. D., Couture, D. E., Mcmullen, K. P., Tatter, S. B., & Morris, P. P. (2014). Definitive treatment of vein of Galen aneurysmal malformation with stereotactic radiosurgery: Report of 2 cases. Journal of neurosurgery, 120(1), 120-125. https://doi.org/10.3171/2013.6.JNS121897