Deletion of 3'-CBFB gene in association with an inversion (16)(p13q22) and a loss of the Y chromosome in a 2-year-old child with acute myelogenous leukemia-M4

Jacqueline R. Batanian, Yufeng Huang, Robert Fallon

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9 Scopus citations


Inversion 16(p13q22) is most commonly associated with acute myelomonocytic leukemia with abnormal eosinophils (M4). In association with this inversion, a proximal deletion at the 16p13 primary arm breakpoint occurs in 20% of cases. We report on a first case of inversion 16 with a distal deletion at the primary arm breakpoint 16q22, detected by using the fluorescent-labeled dual-color probe CBFB. Copyright (C) 2000 Elsevier Science Inc.

Original languageEnglish (US)
Pages (from-to)216-219
Number of pages4
JournalCancer Genetics and Cytogenetics
Issue number2
StatePublished - Nov 1 2000


ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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