Delivery of intraocular triamcinolone acetonide in the treatment of macular edema

Aaron Pickrell, Alon Harris, Sandra Ngo, Annahita Amireskandari, Erin Stewart, Brent Siesky

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Macular edema (ME) is one of the eventual outcomes of various intraocular and systemic pathologies. The pathogenesis for ME is not yet entirely understood; however, some of the common risk factors for its development have been identified. While this investigation will not discuss the numerous etiologies of ME in detail, it appraises the two most widely studied delivery modalities of intraocular corticosteroids in the treatment of ME-intravitreal injection (IVI) and sub-Tenon's infusion (STI). A thorough review of the medical literature was conducted to identify the efficacy and safety of IVI and STI, specifically for the administration of triamcinolone acetonide (TA), in the setting of ME in an attempt to elucidate a preferred steroid delivery modality for treatment of ME.

Original languageEnglish (US)
Pages (from-to)230-242
Number of pages13
JournalPharmaceutics
Volume4
Issue number1
DOIs
StatePublished - Mar 1 2012

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Keywords

  • Corticosteroids
  • Intravitreal injection
  • Macular edema
  • Sub-tenon's injection
  • Triamcinolone

ASJC Scopus subject areas

  • Pharmaceutical Science

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