Delta-1 provides pleasant stem cell environs

Louis Pelus, Pratibha Singh

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In this issue of Blood, Csaszar et al show that in ex vivo cultures of CD341 cells, simultaneous reduction of interleukin-6 receptor (IL-6R) expression on myeloid progenitor cells by Delta-1 treatment combined with removal of soluble IL-6R using a dynamically fed culture system, reduces mature myeloid cell production, leading to enhanced expansion of primitive hematopoietic stem cells.

Original languageEnglish
Pages (from-to)605-606
Number of pages2
JournalBlood
Volume123
Issue number5
DOIs
StatePublished - Jan 30 2014

Fingerprint

Interleukin-6 Receptors
Stem cells
Stem Cells
Myeloid Progenitor Cells
Myeloid Cells
Hematopoietic Stem Cells
Blood
Cell Culture Techniques
Environ

ASJC Scopus subject areas

  • Hematology
  • Biochemistry
  • Cell Biology
  • Immunology

Cite this

Delta-1 provides pleasant stem cell environs. / Pelus, Louis; Singh, Pratibha.

In: Blood, Vol. 123, No. 5, 30.01.2014, p. 605-606.

Research output: Contribution to journalArticle

Pelus, L & Singh, P 2014, 'Delta-1 provides pleasant stem cell environs', Blood, vol. 123, no. 5, pp. 605-606. https://doi.org/10.1182/blood-2013-12-539841
Pelus, Louis ; Singh, Pratibha. / Delta-1 provides pleasant stem cell environs. In: Blood. 2014 ; Vol. 123, No. 5. pp. 605-606.
@article{4c514cd716de45f8b8437beb13f44916,
title = "Delta-1 provides pleasant stem cell environs",
abstract = "In this issue of Blood, Csaszar et al show that in ex vivo cultures of CD341 cells, simultaneous reduction of interleukin-6 receptor (IL-6R) expression on myeloid progenitor cells by Delta-1 treatment combined with removal of soluble IL-6R using a dynamically fed culture system, reduces mature myeloid cell production, leading to enhanced expansion of primitive hematopoietic stem cells.",
author = "Louis Pelus and Pratibha Singh",
year = "2014",
month = "1",
day = "30",
doi = "10.1182/blood-2013-12-539841",
language = "English",
volume = "123",
pages = "605--606",
journal = "Blood",
issn = "0006-4971",
publisher = "American Society of Hematology",
number = "5",

}

TY - JOUR

T1 - Delta-1 provides pleasant stem cell environs

AU - Pelus, Louis

AU - Singh, Pratibha

PY - 2014/1/30

Y1 - 2014/1/30

N2 - In this issue of Blood, Csaszar et al show that in ex vivo cultures of CD341 cells, simultaneous reduction of interleukin-6 receptor (IL-6R) expression on myeloid progenitor cells by Delta-1 treatment combined with removal of soluble IL-6R using a dynamically fed culture system, reduces mature myeloid cell production, leading to enhanced expansion of primitive hematopoietic stem cells.

AB - In this issue of Blood, Csaszar et al show that in ex vivo cultures of CD341 cells, simultaneous reduction of interleukin-6 receptor (IL-6R) expression on myeloid progenitor cells by Delta-1 treatment combined with removal of soluble IL-6R using a dynamically fed culture system, reduces mature myeloid cell production, leading to enhanced expansion of primitive hematopoietic stem cells.

UR - http://www.scopus.com/inward/record.url?scp=84894060023&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84894060023&partnerID=8YFLogxK

U2 - 10.1182/blood-2013-12-539841

DO - 10.1182/blood-2013-12-539841

M3 - Article

VL - 123

SP - 605

EP - 606

JO - Blood

JF - Blood

SN - 0006-4971

IS - 5

ER -