Delta-1 provides pleasant stem cell environs

Louis M. Pelus, Pratibha Singh

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

In this issue of Blood, Csaszar et al show that in ex vivo cultures of CD341 cells, simultaneous reduction of interleukin-6 receptor (IL-6R) expression on myeloid progenitor cells by Delta-1 treatment combined with removal of soluble IL-6R using a dynamically fed culture system, reduces mature myeloid cell production, leading to enhanced expansion of primitive hematopoietic stem cells.

Original languageEnglish (US)
Pages (from-to)605-606
Number of pages2
JournalBlood
Volume123
Issue number5
DOIs
StatePublished - Jan 30 2014

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ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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