Demographics and trends in overweight and obesity in patients at time of kidney transplantation

Allon Friedman, Dana C. Miskulin, Irwin H. Rosenberg, Andrew S. Levey

Research output: Contribution to journalArticle

161 Citations (Scopus)

Abstract

Background: The epidemic of overweight and obesity is one of the most serious public health problems in the United States, although information regarding its effect on chronic kidney transplant patients is sparse. The authors describe the prevalence, demographics, and trends in overweight and obesity at the time of kidney transplantation. Methods: Data were obtained from a national transplant database that included all kidney transplants since 1987. Body mass indices (BMI) at time of transplantation were stratified by demographic categories and year. Trends of overweight and obesity between the general population and subjects undergoing kidney transplantation were compared. Logistic regression analyses were performed to identify variables associated with increased likelihood of being obese. Results: The majority (60%) of subjects at time of transplantation currently are overweight or obese. Between 1987 and 2001, the proportion of obese transplant recipients rose by 116%. The rate of increase was grossly similar to that in the general population. The likelihood of being obese increased with age, female sex, noninsulin-dependent diabetes mellitus, black race, and the more recent the transplant year. Conversely, the proportion of recipients with lower BMI fell by approximately 50%. Conclusions: Overweight and obesity are very prevalent at the time of kidney transplantation and are eclipsing protein-energy malnutrition as the more common nutritional illness. This may have profound negative effects on patient and allograft outcomes. Nephrologists may need to reexamine traditional notions of nutritional disease and therapeutic strategies to more effectively deal with this formidable challenge.

Original languageEnglish
Pages (from-to)480-487
Number of pages8
JournalAmerican Journal of Kidney Diseases
Volume41
Issue number2
DOIs
StatePublished - Feb 1 2003

Fingerprint

Kidney Transplantation
Obesity
Demography
Transplants
Body Mass Index
Transplantation
Kidney
Protein-Energy Malnutrition
Type 2 Diabetes Mellitus
Population
Allografts
Public Health
Logistic Models
Regression Analysis
Databases
Therapeutics

Keywords

  • Body mass index (BMI)
  • Chronic kidney disease (CKD)
  • Malnutrition
  • Obesity
  • Overweight
  • Transplant

ASJC Scopus subject areas

  • Nephrology

Cite this

Demographics and trends in overweight and obesity in patients at time of kidney transplantation. / Friedman, Allon; Miskulin, Dana C.; Rosenberg, Irwin H.; Levey, Andrew S.

In: American Journal of Kidney Diseases, Vol. 41, No. 2, 01.02.2003, p. 480-487.

Research output: Contribution to journalArticle

Friedman, Allon ; Miskulin, Dana C. ; Rosenberg, Irwin H. ; Levey, Andrew S. / Demographics and trends in overweight and obesity in patients at time of kidney transplantation. In: American Journal of Kidney Diseases. 2003 ; Vol. 41, No. 2. pp. 480-487.
@article{5718faa3cd3d455aa793c9b1c349d4f4,
title = "Demographics and trends in overweight and obesity in patients at time of kidney transplantation",
abstract = "Background: The epidemic of overweight and obesity is one of the most serious public health problems in the United States, although information regarding its effect on chronic kidney transplant patients is sparse. The authors describe the prevalence, demographics, and trends in overweight and obesity at the time of kidney transplantation. Methods: Data were obtained from a national transplant database that included all kidney transplants since 1987. Body mass indices (BMI) at time of transplantation were stratified by demographic categories and year. Trends of overweight and obesity between the general population and subjects undergoing kidney transplantation were compared. Logistic regression analyses were performed to identify variables associated with increased likelihood of being obese. Results: The majority (60{\%}) of subjects at time of transplantation currently are overweight or obese. Between 1987 and 2001, the proportion of obese transplant recipients rose by 116{\%}. The rate of increase was grossly similar to that in the general population. The likelihood of being obese increased with age, female sex, noninsulin-dependent diabetes mellitus, black race, and the more recent the transplant year. Conversely, the proportion of recipients with lower BMI fell by approximately 50{\%}. Conclusions: Overweight and obesity are very prevalent at the time of kidney transplantation and are eclipsing protein-energy malnutrition as the more common nutritional illness. This may have profound negative effects on patient and allograft outcomes. Nephrologists may need to reexamine traditional notions of nutritional disease and therapeutic strategies to more effectively deal with this formidable challenge.",
keywords = "Body mass index (BMI), Chronic kidney disease (CKD), Malnutrition, Obesity, Overweight, Transplant",
author = "Allon Friedman and Miskulin, {Dana C.} and Rosenberg, {Irwin H.} and Levey, {Andrew S.}",
year = "2003",
month = "2",
day = "1",
doi = "10.1053/ajkd.2003.50059",
language = "English",
volume = "41",
pages = "480--487",
journal = "American Journal of Kidney Diseases",
issn = "0272-6386",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - Demographics and trends in overweight and obesity in patients at time of kidney transplantation

AU - Friedman, Allon

AU - Miskulin, Dana C.

AU - Rosenberg, Irwin H.

AU - Levey, Andrew S.

PY - 2003/2/1

Y1 - 2003/2/1

N2 - Background: The epidemic of overweight and obesity is one of the most serious public health problems in the United States, although information regarding its effect on chronic kidney transplant patients is sparse. The authors describe the prevalence, demographics, and trends in overweight and obesity at the time of kidney transplantation. Methods: Data were obtained from a national transplant database that included all kidney transplants since 1987. Body mass indices (BMI) at time of transplantation were stratified by demographic categories and year. Trends of overweight and obesity between the general population and subjects undergoing kidney transplantation were compared. Logistic regression analyses were performed to identify variables associated with increased likelihood of being obese. Results: The majority (60%) of subjects at time of transplantation currently are overweight or obese. Between 1987 and 2001, the proportion of obese transplant recipients rose by 116%. The rate of increase was grossly similar to that in the general population. The likelihood of being obese increased with age, female sex, noninsulin-dependent diabetes mellitus, black race, and the more recent the transplant year. Conversely, the proportion of recipients with lower BMI fell by approximately 50%. Conclusions: Overweight and obesity are very prevalent at the time of kidney transplantation and are eclipsing protein-energy malnutrition as the more common nutritional illness. This may have profound negative effects on patient and allograft outcomes. Nephrologists may need to reexamine traditional notions of nutritional disease and therapeutic strategies to more effectively deal with this formidable challenge.

AB - Background: The epidemic of overweight and obesity is one of the most serious public health problems in the United States, although information regarding its effect on chronic kidney transplant patients is sparse. The authors describe the prevalence, demographics, and trends in overweight and obesity at the time of kidney transplantation. Methods: Data were obtained from a national transplant database that included all kidney transplants since 1987. Body mass indices (BMI) at time of transplantation were stratified by demographic categories and year. Trends of overweight and obesity between the general population and subjects undergoing kidney transplantation were compared. Logistic regression analyses were performed to identify variables associated with increased likelihood of being obese. Results: The majority (60%) of subjects at time of transplantation currently are overweight or obese. Between 1987 and 2001, the proportion of obese transplant recipients rose by 116%. The rate of increase was grossly similar to that in the general population. The likelihood of being obese increased with age, female sex, noninsulin-dependent diabetes mellitus, black race, and the more recent the transplant year. Conversely, the proportion of recipients with lower BMI fell by approximately 50%. Conclusions: Overweight and obesity are very prevalent at the time of kidney transplantation and are eclipsing protein-energy malnutrition as the more common nutritional illness. This may have profound negative effects on patient and allograft outcomes. Nephrologists may need to reexamine traditional notions of nutritional disease and therapeutic strategies to more effectively deal with this formidable challenge.

KW - Body mass index (BMI)

KW - Chronic kidney disease (CKD)

KW - Malnutrition

KW - Obesity

KW - Overweight

KW - Transplant

UR - http://www.scopus.com/inward/record.url?scp=0037311062&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037311062&partnerID=8YFLogxK

U2 - 10.1053/ajkd.2003.50059

DO - 10.1053/ajkd.2003.50059

M3 - Article

C2 - 12552513

AN - SCOPUS:0037311062

VL - 41

SP - 480

EP - 487

JO - American Journal of Kidney Diseases

JF - American Journal of Kidney Diseases

SN - 0272-6386

IS - 2

ER -