Dentifrice fluoride and abrasivity interplay on artificial caries lesions

Hani M. Nassar, Frank Lippert, George J. Eckert, Anderson Hara

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Incipient caries lesions on smooth surfaces may be subjected to toothbrushing, potentially leading to remineralization and/or abrasive wear. The interplay of dentifrice abrasivity and fluoride on this process is largely unknown and was investigated on three artificially created lesions with different mineral content/distribution. 120 bovine enamel specimens were randomly allocated to 12 groups (n = 10), resulting from the association of (1) lesion type [methylcellulose acid gel (MeC); carboxymethylcellulose solution (CMC); hydroxyethylcellulose gel (HEC)], (2) slurry abrasive level [low (REA 4/RDA 69); high (REA 7/RDA 208)], and (3) fluoride concentration [0/275 ppm (14.5 m M) F as NaF]. After lesion creation, specimens were brushed in an automated brushing machine with the test slurries (50 strokes 2×/day). Specimens were kept in artificial saliva in between brushings and overnight. Enamel surface loss (SL) was determined by optical profilometry after lesion creation, 1, 3 and 5 days. Two enamel sections (from baseline and post-brushing areas) were obtained and analyzed microradiographically. Data were analyzed by analysis of variance and Tukey's tests (α = 5%). Brushing with high-abrasive slurry caused more SL than brushing with low-abrasive slurry. For MeC and CMC lesions, fluoride had a protective effect on SL from day 3 on. Furthermore, for MeC and CMC, there was a significant mineral gain in the remaining lesions except when brushed with high-abrasive slurries and 0 ppm F. For HEC, a significant mineral gain took place when low-abrasive slurry was used with fluoride. The tested lesions responded differently to the toothbrushing procedures. Both slurry fluoride content and abrasivity directly impacted SL and mineral gain of enamel caries lesions.

Original languageEnglish (US)
Pages (from-to)557-565
Number of pages9
JournalCaries Research
Volume48
Issue number6
DOIs
StatePublished - Dec 2 2014

Fingerprint

Dentifrices
Fluorides
Dental Enamel
Carboxymethylcellulose Sodium
Minerals
Toothbrushing
Gels
Artificial Saliva
Methylcellulose
Analysis of Variance
Stroke
Acids

Keywords

  • Abrasion
  • Abrasives
  • Dentifrice
  • Fluoride
  • Incipient caries
  • Remineralization

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Dentifrice fluoride and abrasivity interplay on artificial caries lesions. / Nassar, Hani M.; Lippert, Frank; Eckert, George J.; Hara, Anderson.

In: Caries Research, Vol. 48, No. 6, 02.12.2014, p. 557-565.

Research output: Contribution to journalArticle

Nassar, Hani M. ; Lippert, Frank ; Eckert, George J. ; Hara, Anderson. / Dentifrice fluoride and abrasivity interplay on artificial caries lesions. In: Caries Research. 2014 ; Vol. 48, No. 6. pp. 557-565.
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abstract = "Incipient caries lesions on smooth surfaces may be subjected to toothbrushing, potentially leading to remineralization and/or abrasive wear. The interplay of dentifrice abrasivity and fluoride on this process is largely unknown and was investigated on three artificially created lesions with different mineral content/distribution. 120 bovine enamel specimens were randomly allocated to 12 groups (n = 10), resulting from the association of (1) lesion type [methylcellulose acid gel (MeC); carboxymethylcellulose solution (CMC); hydroxyethylcellulose gel (HEC)], (2) slurry abrasive level [low (REA 4/RDA 69); high (REA 7/RDA 208)], and (3) fluoride concentration [0/275 ppm (14.5 m M) F as NaF]. After lesion creation, specimens were brushed in an automated brushing machine with the test slurries (50 strokes 2×/day). Specimens were kept in artificial saliva in between brushings and overnight. Enamel surface loss (SL) was determined by optical profilometry after lesion creation, 1, 3 and 5 days. Two enamel sections (from baseline and post-brushing areas) were obtained and analyzed microradiographically. Data were analyzed by analysis of variance and Tukey's tests (α = 5{\%}). Brushing with high-abrasive slurry caused more SL than brushing with low-abrasive slurry. For MeC and CMC lesions, fluoride had a protective effect on SL from day 3 on. Furthermore, for MeC and CMC, there was a significant mineral gain in the remaining lesions except when brushed with high-abrasive slurries and 0 ppm F. For HEC, a significant mineral gain took place when low-abrasive slurry was used with fluoride. The tested lesions responded differently to the toothbrushing procedures. Both slurry fluoride content and abrasivity directly impacted SL and mineral gain of enamel caries lesions.",
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