Depressed mood in informal caregivers of individuals with mild cognitive impairment

Yueh Feng Yvonne Lu, Mary Guerriero Austrom, Susan M. Perkins, Bakas Tamilyn, Martin R. Farlow, Feng He, Shelia Jin, Anthony Gamst

Research output: Contribution to journalArticle

35 Scopus citations


This study estimates the prevalence of depressed mood in caregivers of individuals with mild cognitive impairment (MCI) and assesses whether demographics, stressors, intrapsychic strain, and gain are associated with depressed mood. A secondary analysis of baseline data from the Alzheimer's Disease Cooperative Study MCI trial was conducted using a cross-sectional, correlational design. Descriptive statistics to estimate the prevalence of caregiver depressed mood and univariate and blockwise logistic regression analyses were used. The prevalence of depressed mood in 769 caregivers was 24.6% (95% confidence interval, 21.5-27.7). The odds of being depressed were significantly higher in younger, nonspousal caregivers with less education, who cared for MCI patients with lower activities of daily living functioning, and who perceived greater relational deprivation, higher levels of self-loss, and personal gain. Controlling for relevant variables, relational deprivation and caregiver education continued to be significantly associated with depressed mood. Relational deprivation may be important for future interventions.

Original languageEnglish (US)
Pages (from-to)273-285
Number of pages13
JournalAmerican Journal of Alzheimer's Disease and Other Dementias
Issue number4
StatePublished - Jan 1 2007


  • Caregiving
  • Depression
  • Mild cognitive impairment
  • Stress

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Geriatrics and Gerontology

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