Designing inhibitors of the metalloproteinase superfamily: Comparative analysis of representative structures

Venugopal Dhanaraj, Qizhuang Ye, Linda L. Johnson, Donald J. Hupe, Daniel F. Ortwine, James B. Dunbar, J. R. Rubin, A. Pavlovsky, Christine Humblet, Tom L. Blundell

Research output: Contribution to journalArticle

9 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)3-14
Number of pages12
JournalDrug Design and Discovery
Volume13
Issue number3-4
StatePublished - 1996
Externally publishedYes

Fingerprint

Molecular Sequence Data
Metalloendopeptidases
Thermolysin
Secondary Protein Structure
Matrix Metalloproteinase 3
Molecular Models
Drug Design
Metalloproteases
Collagenases
Matrix Metalloproteinases
Catalysis
Tertiary Protein Structure
Protein Binding
Zinc
Binding Sites

Keywords

  • Matrix metalloproteinases
  • Metzincins
  • Stromelysin
  • Structural comparisons
  • Zinc metalloproteinase superfamily

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

Cite this

Dhanaraj, V., Ye, Q., Johnson, L. L., Hupe, D. J., Ortwine, D. F., Dunbar, J. B., ... Blundell, T. L. (1996). Designing inhibitors of the metalloproteinase superfamily: Comparative analysis of representative structures. Drug Design and Discovery, 13(3-4), 3-14.

Designing inhibitors of the metalloproteinase superfamily : Comparative analysis of representative structures. / Dhanaraj, Venugopal; Ye, Qizhuang; Johnson, Linda L.; Hupe, Donald J.; Ortwine, Daniel F.; Dunbar, James B.; Rubin, J. R.; Pavlovsky, A.; Humblet, Christine; Blundell, Tom L.

In: Drug Design and Discovery, Vol. 13, No. 3-4, 1996, p. 3-14.

Research output: Contribution to journalArticle

Dhanaraj, V, Ye, Q, Johnson, LL, Hupe, DJ, Ortwine, DF, Dunbar, JB, Rubin, JR, Pavlovsky, A, Humblet, C & Blundell, TL 1996, 'Designing inhibitors of the metalloproteinase superfamily: Comparative analysis of representative structures', Drug Design and Discovery, vol. 13, no. 3-4, pp. 3-14.
Dhanaraj, Venugopal ; Ye, Qizhuang ; Johnson, Linda L. ; Hupe, Donald J. ; Ortwine, Daniel F. ; Dunbar, James B. ; Rubin, J. R. ; Pavlovsky, A. ; Humblet, Christine ; Blundell, Tom L. / Designing inhibitors of the metalloproteinase superfamily : Comparative analysis of representative structures. In: Drug Design and Discovery. 1996 ; Vol. 13, No. 3-4. pp. 3-14.
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