Detection of left ventricular asynergy by echocardiography

J. J. Jacobs, Harvey Feigenbaum, B. C. Corya, J. F. Phillips

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

The purpose of this study was to determine if echocardiography could detect left ventricular asynergy. Forty eight patients underwent selective coronary arteriography and cineventriculography for the evaluation of chest pain. Four patients were studied twice: three before and after myocardial revascularization and one before and after an intervening myocardial infarction. Echocardiographic M-mode scans were registered on a strip chart as the left ventricle was scanned with an ultrasonic beam from the aortic root to the region of the posterior papillary muscle approximately 18 hrs prior to the catheterization studies. Ten of the forty eight patients had no evidence of coronary artery disease. All ten patients had normal ventriculograms in right anterior oblique projection and their echocardiographic scans showed all areas of the left ventricular posterior wall endocardium to move anteriorly 0.9-1.4 cm (mean 1.2 cm) and all parts of the left side of the interventricular septum to move posteriorly 0.3-0.8 cm (mean 0.5 cm) during systole. The 38 patients with significant obstructive coronary artery disease had a total of 42 studies; 25 of these studies showed left ventricular asynergy on the ventriculogram taken in right anterior oblique. The echocardiograms associated with all but one of these studies demonstrating left ventricular asynergy had abnormal motion of some part of the interventricular septum and/or left ventricular posterior wall. Seventeen studies in patients with significant coronary artery disease did not exhibit left ventricular asynergy on the ventriculogram but eight of these studies were associated with distinctly abnormal echocardiograms. None of the ten patients with significant coronary artery disease and normal echocardiograms had evidence of transmural infarction on their electrocardiograms. Echocardiographic abnormalities correlated with the anatomic area predicted by the myocardial infarction pattern on the electrocardiogram in 18 of 20 patients. All patients demonstrating abnormal echographic interventricular septal motion had a significant obstructive lesion in the left anterior descending coronary artery, echographically recorded interventricular septal motion was invariably normal. On the other hand, eight patients had significant obstruction in their left anterior descending coronary artery and their echographic interventricular septal motion was normal. The results of this correlative study indicate that M-mode echocardiographic scans can detect left ventricular asynergy and may possibly predict regional myocardial involvement in coronary artery disease.

Original languageEnglish
Pages (from-to)263-271
Number of pages9
JournalCirculation
Volume48
Issue number2
StatePublished - 1973

Fingerprint

Echocardiography
Coronary Artery Disease
Coronary Vessels
Electrocardiography
Myocardial Infarction
Endocardium
Myocardial Revascularization
Papillary Muscles
Systole
Chest Pain
Ultrasonics
Catheterization
Infarction
Heart Ventricles
Angiography

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Jacobs, J. J., Feigenbaum, H., Corya, B. C., & Phillips, J. F. (1973). Detection of left ventricular asynergy by echocardiography. Circulation, 48(2), 263-271.

Detection of left ventricular asynergy by echocardiography. / Jacobs, J. J.; Feigenbaum, Harvey; Corya, B. C.; Phillips, J. F.

In: Circulation, Vol. 48, No. 2, 1973, p. 263-271.

Research output: Contribution to journalArticle

Jacobs, JJ, Feigenbaum, H, Corya, BC & Phillips, JF 1973, 'Detection of left ventricular asynergy by echocardiography', Circulation, vol. 48, no. 2, pp. 263-271.
Jacobs JJ, Feigenbaum H, Corya BC, Phillips JF. Detection of left ventricular asynergy by echocardiography. Circulation. 1973;48(2):263-271.
Jacobs, J. J. ; Feigenbaum, Harvey ; Corya, B. C. ; Phillips, J. F. / Detection of left ventricular asynergy by echocardiography. In: Circulation. 1973 ; Vol. 48, No. 2. pp. 263-271.
@article{c40f65a78e4c4fb6adb7203a360f00be,
title = "Detection of left ventricular asynergy by echocardiography",
abstract = "The purpose of this study was to determine if echocardiography could detect left ventricular asynergy. Forty eight patients underwent selective coronary arteriography and cineventriculography for the evaluation of chest pain. Four patients were studied twice: three before and after myocardial revascularization and one before and after an intervening myocardial infarction. Echocardiographic M-mode scans were registered on a strip chart as the left ventricle was scanned with an ultrasonic beam from the aortic root to the region of the posterior papillary muscle approximately 18 hrs prior to the catheterization studies. Ten of the forty eight patients had no evidence of coronary artery disease. All ten patients had normal ventriculograms in right anterior oblique projection and their echocardiographic scans showed all areas of the left ventricular posterior wall endocardium to move anteriorly 0.9-1.4 cm (mean 1.2 cm) and all parts of the left side of the interventricular septum to move posteriorly 0.3-0.8 cm (mean 0.5 cm) during systole. The 38 patients with significant obstructive coronary artery disease had a total of 42 studies; 25 of these studies showed left ventricular asynergy on the ventriculogram taken in right anterior oblique. The echocardiograms associated with all but one of these studies demonstrating left ventricular asynergy had abnormal motion of some part of the interventricular septum and/or left ventricular posterior wall. Seventeen studies in patients with significant coronary artery disease did not exhibit left ventricular asynergy on the ventriculogram but eight of these studies were associated with distinctly abnormal echocardiograms. None of the ten patients with significant coronary artery disease and normal echocardiograms had evidence of transmural infarction on their electrocardiograms. Echocardiographic abnormalities correlated with the anatomic area predicted by the myocardial infarction pattern on the electrocardiogram in 18 of 20 patients. All patients demonstrating abnormal echographic interventricular septal motion had a significant obstructive lesion in the left anterior descending coronary artery, echographically recorded interventricular septal motion was invariably normal. On the other hand, eight patients had significant obstruction in their left anterior descending coronary artery and their echographic interventricular septal motion was normal. The results of this correlative study indicate that M-mode echocardiographic scans can detect left ventricular asynergy and may possibly predict regional myocardial involvement in coronary artery disease.",
author = "Jacobs, {J. J.} and Harvey Feigenbaum and Corya, {B. C.} and Phillips, {J. F.}",
year = "1973",
language = "English",
volume = "48",
pages = "263--271",
journal = "Circulation",
issn = "0009-7322",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Detection of left ventricular asynergy by echocardiography

AU - Jacobs, J. J.

AU - Feigenbaum, Harvey

AU - Corya, B. C.

AU - Phillips, J. F.

PY - 1973

Y1 - 1973

N2 - The purpose of this study was to determine if echocardiography could detect left ventricular asynergy. Forty eight patients underwent selective coronary arteriography and cineventriculography for the evaluation of chest pain. Four patients were studied twice: three before and after myocardial revascularization and one before and after an intervening myocardial infarction. Echocardiographic M-mode scans were registered on a strip chart as the left ventricle was scanned with an ultrasonic beam from the aortic root to the region of the posterior papillary muscle approximately 18 hrs prior to the catheterization studies. Ten of the forty eight patients had no evidence of coronary artery disease. All ten patients had normal ventriculograms in right anterior oblique projection and their echocardiographic scans showed all areas of the left ventricular posterior wall endocardium to move anteriorly 0.9-1.4 cm (mean 1.2 cm) and all parts of the left side of the interventricular septum to move posteriorly 0.3-0.8 cm (mean 0.5 cm) during systole. The 38 patients with significant obstructive coronary artery disease had a total of 42 studies; 25 of these studies showed left ventricular asynergy on the ventriculogram taken in right anterior oblique. The echocardiograms associated with all but one of these studies demonstrating left ventricular asynergy had abnormal motion of some part of the interventricular septum and/or left ventricular posterior wall. Seventeen studies in patients with significant coronary artery disease did not exhibit left ventricular asynergy on the ventriculogram but eight of these studies were associated with distinctly abnormal echocardiograms. None of the ten patients with significant coronary artery disease and normal echocardiograms had evidence of transmural infarction on their electrocardiograms. Echocardiographic abnormalities correlated with the anatomic area predicted by the myocardial infarction pattern on the electrocardiogram in 18 of 20 patients. All patients demonstrating abnormal echographic interventricular septal motion had a significant obstructive lesion in the left anterior descending coronary artery, echographically recorded interventricular septal motion was invariably normal. On the other hand, eight patients had significant obstruction in their left anterior descending coronary artery and their echographic interventricular septal motion was normal. The results of this correlative study indicate that M-mode echocardiographic scans can detect left ventricular asynergy and may possibly predict regional myocardial involvement in coronary artery disease.

AB - The purpose of this study was to determine if echocardiography could detect left ventricular asynergy. Forty eight patients underwent selective coronary arteriography and cineventriculography for the evaluation of chest pain. Four patients were studied twice: three before and after myocardial revascularization and one before and after an intervening myocardial infarction. Echocardiographic M-mode scans were registered on a strip chart as the left ventricle was scanned with an ultrasonic beam from the aortic root to the region of the posterior papillary muscle approximately 18 hrs prior to the catheterization studies. Ten of the forty eight patients had no evidence of coronary artery disease. All ten patients had normal ventriculograms in right anterior oblique projection and their echocardiographic scans showed all areas of the left ventricular posterior wall endocardium to move anteriorly 0.9-1.4 cm (mean 1.2 cm) and all parts of the left side of the interventricular septum to move posteriorly 0.3-0.8 cm (mean 0.5 cm) during systole. The 38 patients with significant obstructive coronary artery disease had a total of 42 studies; 25 of these studies showed left ventricular asynergy on the ventriculogram taken in right anterior oblique. The echocardiograms associated with all but one of these studies demonstrating left ventricular asynergy had abnormal motion of some part of the interventricular septum and/or left ventricular posterior wall. Seventeen studies in patients with significant coronary artery disease did not exhibit left ventricular asynergy on the ventriculogram but eight of these studies were associated with distinctly abnormal echocardiograms. None of the ten patients with significant coronary artery disease and normal echocardiograms had evidence of transmural infarction on their electrocardiograms. Echocardiographic abnormalities correlated with the anatomic area predicted by the myocardial infarction pattern on the electrocardiogram in 18 of 20 patients. All patients demonstrating abnormal echographic interventricular septal motion had a significant obstructive lesion in the left anterior descending coronary artery, echographically recorded interventricular septal motion was invariably normal. On the other hand, eight patients had significant obstruction in their left anterior descending coronary artery and their echographic interventricular septal motion was normal. The results of this correlative study indicate that M-mode echocardiographic scans can detect left ventricular asynergy and may possibly predict regional myocardial involvement in coronary artery disease.

UR - http://www.scopus.com/inward/record.url?scp=0015879150&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015879150&partnerID=8YFLogxK

M3 - Article

VL - 48

SP - 263

EP - 271

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 2

ER -