Determination of zero-field size percent depth doses and tissue maximum ratios for stereotactic radiosurgery and IMRT dosimetry

Comparison between experimental measurements and Monte Carlo simulation

Chee Wai Cheng, Sang Hyun Cho, Michael Taylor, Indra J. Das

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

In this study, zero-field percent depth dose (PDD) and tissue maximum ratio (TMR) for 6 MV x rays have been determined by extrapolation from dosimetric measurements over the field size range 1×1-10×10 cm2. The key to small field dosimetry is the selection of a proper dosimeter for the measurements, as well as the alignment of the detector with the central axis (CAX) of beam. The measured PDD results are compared with those obtained from Monte Carlo (MC) simulation to examine the consistency and integrity of the measured data from which the zero-field PDD is extrapolated. Of the six most commonly used dosimeters in the clinic, the stereotactic diode field detector (SFD), the PTW Pinpoint, and the Exradin A14 are the most consistent and produce results within 2% of each other over the entire field size range 1×1-40×40 cm2. Although the diamond detector has the smallest sensitive volume, it is the least stable and tends to disagree with all other dosimeters by more than 10%. The zero-field PDD data extrapolated from larger field measurements obtained with the SFD are in good agreement with the MC results. The extrapolated and MC data agree within 2.5% over the clinical depth range (dmax -30 cm), when the MC data for the zero field are derived from a 1×1 cm2 field simulation using a miniphantom (1×1×48 cm3). The agreement between the measured PDD and the MC data based on a full phantom (48×48×48 cm3) simulation is fairly good within 1% at shallow depths to approximately 5% at 30 cm. Our results seem to indicate that zero-field TMR can be accurately calculated from PDD measurements with a proper choice of detector and a careful alignment of detector axis with the CAX.

Original languageEnglish (US)
Pages (from-to)3149-3157
Number of pages9
JournalMedical Physics
Volume34
Issue number8
DOIs
StatePublished - 2007
Externally publishedYes

Fingerprint

Radiosurgery
Diamond
X-Rays
Radiation Dosimeters

Keywords

  • IMRT
  • Monte Carlo simulation
  • Small field dosimetry
  • Zero field dosimetry

ASJC Scopus subject areas

  • Biophysics

Cite this

Determination of zero-field size percent depth doses and tissue maximum ratios for stereotactic radiosurgery and IMRT dosimetry : Comparison between experimental measurements and Monte Carlo simulation. / Cheng, Chee Wai; Hyun Cho, Sang; Taylor, Michael; Das, Indra J.

In: Medical Physics, Vol. 34, No. 8, 2007, p. 3149-3157.

Research output: Contribution to journalArticle

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abstract = "In this study, zero-field percent depth dose (PDD) and tissue maximum ratio (TMR) for 6 MV x rays have been determined by extrapolation from dosimetric measurements over the field size range 1×1-10×10 cm2. The key to small field dosimetry is the selection of a proper dosimeter for the measurements, as well as the alignment of the detector with the central axis (CAX) of beam. The measured PDD results are compared with those obtained from Monte Carlo (MC) simulation to examine the consistency and integrity of the measured data from which the zero-field PDD is extrapolated. Of the six most commonly used dosimeters in the clinic, the stereotactic diode field detector (SFD), the PTW Pinpoint, and the Exradin A14 are the most consistent and produce results within 2{\%} of each other over the entire field size range 1×1-40×40 cm2. Although the diamond detector has the smallest sensitive volume, it is the least stable and tends to disagree with all other dosimeters by more than 10{\%}. The zero-field PDD data extrapolated from larger field measurements obtained with the SFD are in good agreement with the MC results. The extrapolated and MC data agree within 2.5{\%} over the clinical depth range (dmax -30 cm), when the MC data for the zero field are derived from a 1×1 cm2 field simulation using a miniphantom (1×1×48 cm3). The agreement between the measured PDD and the MC data based on a full phantom (48×48×48 cm3) simulation is fairly good within 1{\%} at shallow depths to approximately 5{\%} at 30 cm. Our results seem to indicate that zero-field TMR can be accurately calculated from PDD measurements with a proper choice of detector and a careful alignment of detector axis with the CAX.",
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