Developmental aspects of panic and related anxiety disorders

Jacqueline A. Hobbs, Anantha Shekhar

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Panic and related anxiety disorders are common psychiatric disorders. Both genetic and environmental factors appear to contribute to their development. Multiple brain regions including the amygdala, hippocampus, and frontal cortex, as well as associated neurotransmitter and neuroendocrine systems have been implicated in the development of these disorders. Early life stressors such as maternal separation, inflammation, and infection also appear to play important roles. This review will discuss recent animal and human studies that are beginning to elucidate the neurodevelopmental mechanisms of panic and anxiety disorders.

Original languageEnglish (US)
Pages (from-to)72-80
Number of pages9
JournalNeuroembryology
Volume2
Issue number2
DOIs
StatePublished - Dec 11 2003

Keywords

  • Amygdala
  • Fear
  • Hippocampus
  • Stress
  • Transgenics

ASJC Scopus subject areas

  • Developmental Biology
  • Neuroscience(all)
  • Developmental Neuroscience
  • Embryology

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