Diabetes mellitus and cerebrovascular disease: Prevalence of carotid artery occlusive disease and associated risk factors in 482 adult diabetic patients

T. W. Kuebler, P. J. Bendick, S. E. Fineberg, Omkar Markand, J. A. Norton, F. N. Vinicor, C. M. Clark

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The prevalence of carotid artery occlusive disease (CAOD) in a population of adults with diabetes mellitus was determined, and factors associated with its presence were identified. By oculoplethysmography and phonoangiography, 20% of the population studied had detectable CAOD. Univariate analyses revealed that patients with CAOD had a higher prevalence of retinopathy proteinuria, a slower mean conduction velocity in two of three nerves tested, and more atherosclerosis in the leg arteries. Furthermore, increased age, higher cholesterol, lower fasting insulin, higher systolic blood pressure, and less adiposity were associated with the presence of CAOD. Sex, race, type of diabetes (types I or II), duration of diabetes, and measures of glycemia were not related to CAOD. When 10 variables were analyzed by multivariate methods, higher systolic blood pressure, higher cholesterol, and reduced adiposity were found to be the combination most significantly related to CAOD.

Original languageEnglish (US)
Pages (from-to)274-278
Number of pages5
JournalDiabetes Care
Volume6
Issue number3
StatePublished - 1983
Externally publishedYes

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Cerebrovascular Disorders
Carotid Artery Diseases
Diabetes Mellitus
Adiposity
Cholesterol
Blood Pressure
Hypertension
Type 1 Diabetes Mellitus
Proteinuria
Type 2 Diabetes Mellitus
Population
Fasting
Leg
Atherosclerosis
Arteries
Insulin

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Kuebler, T. W., Bendick, P. J., Fineberg, S. E., Markand, O., Norton, J. A., Vinicor, F. N., & Clark, C. M. (1983). Diabetes mellitus and cerebrovascular disease: Prevalence of carotid artery occlusive disease and associated risk factors in 482 adult diabetic patients. Diabetes Care, 6(3), 274-278.

Diabetes mellitus and cerebrovascular disease : Prevalence of carotid artery occlusive disease and associated risk factors in 482 adult diabetic patients. / Kuebler, T. W.; Bendick, P. J.; Fineberg, S. E.; Markand, Omkar; Norton, J. A.; Vinicor, F. N.; Clark, C. M.

In: Diabetes Care, Vol. 6, No. 3, 1983, p. 274-278.

Research output: Contribution to journalArticle

Kuebler, T. W. ; Bendick, P. J. ; Fineberg, S. E. ; Markand, Omkar ; Norton, J. A. ; Vinicor, F. N. ; Clark, C. M. / Diabetes mellitus and cerebrovascular disease : Prevalence of carotid artery occlusive disease and associated risk factors in 482 adult diabetic patients. In: Diabetes Care. 1983 ; Vol. 6, No. 3. pp. 274-278.
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