Diagnosis and Staging of Premalignant and Early Malignant Diseases

Ihab I. El Hajj, John M. Dewitt, Gregory A. Coté

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The pathogenesis, natural course, and optimal diagnostic and therapeutic approach for premalignant and early malignant lesions of the periampullary region and extrahepatic biliary tree remain under debate. Their typically aggressive biology mandates an early and accurate diagnosis of these lesions. In this chapter, we describe important clinical features and the role and limitations of endoscopic modalities including direct inspection, tissue sampling, endoscopic ultrasound (EUS), and endoscopic retrograde cholangiopancreatography (ERCP). Future advances in EUS and ERCP may augment their role in early diagnosis and treatment of malignant and premalignant lesions of extrahepatic biliary tree. This edition first published 2013

Original languageEnglish (US)
Title of host publicationGastrointestinal Endoscopy in the Cancer Patient
PublisherJohn Wiley and Sons
Number of pages14
ISBN (Print)9780470672464
StatePublished - Feb 26 2013


  • Ampullary tumors
  • Cholangiocarcinoma
  • Endoscopic retrograde cholangiopancreatography
  • Endoscopic ultrasound
  • Gallbladder lesions
  • Intraductal ultrasound
  • Magnetic resonance cholangiopancreatography
  • Primary sclerosing cholangitis

ASJC Scopus subject areas

  • Medicine(all)

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