Diagnosis and treatment of early lung cancer: As it stands today

Francis D. Sheski, Praveen N. Mathur

Research output: Contribution to journalReview article

6 Scopus citations


Treatment of "early" stage lung cancer should offer the patient the best chance for cure. Disease-free survival after surgical resection of lung carcinoma in situ has been reported as over 90%. For "microinvasive" lung cancer it may be similar. After resection of stage IA non-small cell lung cancer, survival at 5 years is ∼60 to 70%. If endoscopic or bronchoscopic treatments of early stage lung cancer can offer similar disease-free survival with less perioperative mortality, morbidity, and cost, then they may be alternative front-line therapies. Regardless of therapeutic choice, the initial hurdle is developing a practical detection method for early stage disease. This article reviews early stage lung cancer detection by fluorescence bronchoscopy and potential treatment by the endoscopic techniques of photodynamic therapy, brachytherapy, neodymium:yttrium-aluminum-garnet (Nd:YAG) laser, electrocautery, and cryotherapy.

Original languageEnglish (US)
Pages (from-to)387-397
Number of pages11
JournalSeminars in Respiratory and Critical Care Medicine
Issue number4
StatePublished - Aug 1 2004


  • Argon plasma coagulation
  • Cryotherapy
  • Electrocautery
  • Photodynamic therapy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Critical Care

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