Diagnosis and treatment of early lung cancer: As it stands today

Francis Sheski, Praveen N. Mathur

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Treatment of "early" stage lung cancer should offer the patient the best chance for cure. Disease-free survival after surgical resection of lung carcinoma in situ has been reported as over 90%. For "microinvasive" lung cancer it may be similar. After resection of stage IA non-small cell lung cancer, survival at 5 years is ∼60 to 70%. If endoscopic or bronchoscopic treatments of early stage lung cancer can offer similar disease-free survival with less perioperative mortality, morbidity, and cost, then they may be alternative front-line therapies. Regardless of therapeutic choice, the initial hurdle is developing a practical detection method for early stage disease. This article reviews early stage lung cancer detection by fluorescence bronchoscopy and potential treatment by the endoscopic techniques of photodynamic therapy, brachytherapy, neodymium:yttrium-aluminum-garnet (Nd:YAG) laser, electrocautery, and cryotherapy.

Original languageEnglish
Pages (from-to)387-397
Number of pages11
JournalSeminars in Respiratory and Critical Care Medicine
Volume25
Issue number4
DOIs
StatePublished - Aug 2004

Fingerprint

Lung Neoplasms
Disease-Free Survival
Therapeutics
Neodymium
Electrocoagulation
Cryotherapy
Carcinoma in Situ
Solid-State Lasers
Brachytherapy
Photochemotherapy
Bronchoscopy
Non-Small Cell Lung Carcinoma
Fluorescence
Morbidity
Costs and Cost Analysis
Lung
Survival
Mortality

Keywords

  • Argon plasma coagulation
  • Cryotherapy
  • Electrocautery
  • Photodynamic therapy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Critical Care

Cite this

Diagnosis and treatment of early lung cancer : As it stands today. / Sheski, Francis; Mathur, Praveen N.

In: Seminars in Respiratory and Critical Care Medicine, Vol. 25, No. 4, 08.2004, p. 387-397.

Research output: Contribution to journalArticle

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