Diagnostic accuracy of left ventricular function for identifying sepsis among emergency department patients with nontraumatic symptomatic undifferentiated hypotension

Alan E. Jones, Patrick A. Craddock, Vivek S. Tayal, Jeffrey Kline

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

The hypothesis of this study states that in emergency department (ED) patients with nontraumatic symptomatic hypotension, the presence of hyperdynamic left ventricular function (LVF) is specific for sepsis as the etiology of shock. We performed a secondary analysis of patients with nontraumatic symptomatic hypotension enrolled in a randomized, clinical diagnostic trial. The study was done in an urban tertiary ED with a census over 100,000 visits per year. Inclusion criteria were nontrauma ED patients aged >17 years, initial vital signs consistent with shock (systolic blood pressure 1.0), and agreement of two independent observers for one sign and symptom of circulatory shock. All patients underwent focused ED echocardiography (echo) during initial resuscitation. Echos were reviewed post-hoc by a blinded physician and categorized by qualitative LVF as hyperdynamic (ejection fraction [EF] >55%), normal to moderate impairment (EF 30%-55%), and severe impairment (EF

Original languageEnglish (US)
Pages (from-to)513-517
Number of pages5
JournalShock
Volume24
Issue number6
DOIs
StatePublished - Jan 2006
Externally publishedYes

Fingerprint

Left Ventricular Function
Hypotension
Hospital Emergency Service
Sepsis
Shock
Blood Pressure
Vital Signs
Censuses
Resuscitation
Signs and Symptoms
Echocardiography
Randomized Controlled Trials
Physicians

Keywords

  • Hypotension
  • Sensitivity
  • Sepsis
  • Shock
  • Specificity
  • Ultrasound

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Physiology

Cite this

Diagnostic accuracy of left ventricular function for identifying sepsis among emergency department patients with nontraumatic symptomatic undifferentiated hypotension. / Jones, Alan E.; Craddock, Patrick A.; Tayal, Vivek S.; Kline, Jeffrey.

In: Shock, Vol. 24, No. 6, 01.2006, p. 513-517.

Research output: Contribution to journalArticle

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