Diagnostic laparoscopy for periampullary and pancreatic cancer: What is the true benefit?

Christopher J. Barreiro, Keith D. Lillemoe, Leonidas G. Koniaris, Taylor A. Sohn, Charles J. Yeo, Jo Ann Coleman, Elliot K. Fishman, John L. Cameron

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62 Scopus citations

Abstract

The role of diagnostic laparoscopy in patients with periampullary and pancreatic malignancies is controversial. A retrospective review was performed including all patients (n = 188) with a periampullary or pancreatic malignancy who underwent both CT and laparotomy at our institution between January 1997 and December 1999. The overall resectability rate for all periampullary cancers was 67.3% (115 of 171 patients). This compared favorably with the resectability rate for cancers of the pancreatic body and tail (3 of 17 patients, 17.6%; P < 0.01 vs. periampullary cancers). Fifty percent of patients with periampullary cancers were unresectable because of metastatic disease, whereas metastatic disease precluded resection in 64.3% of patients with cancers of the pancreatic body and tail. After patients undergoing operative palliation were eliminated, a nontherapeutic laparotomy would have been precluded by the use of diagnostic laparoscopy in only 2.3% of patients with periampullary cancers (4 of 171 patients). In contrast, 6 (35.3%) of 17 patients with cancers of the pancreatic body and tail underwent a nontherapeutic laparotomy (P < 0.01 vs. periampullary cancers). One hundred fifty-eight (84%) of the 188 CT reports reviewed could be definitively categorized as either "likely to be resectable" or "likely to be unresectable." The remaining 16% were equivocal. Of the 107 patients categorized as likely to be resectable, 89 were actually resected (83.2%). In contrast, only 10 of the 51 patients categorized as likely to be unresectable could be resected (19.6%).

Original languageEnglish (US)
Pages (from-to)75-81
Number of pages7
JournalJournal of Gastrointestinal Surgery
Volume6
Issue number1
DOIs
StatePublished - Jan 1 2002

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Keywords

  • Diagnostic laparoscopy
  • Pancreatic cancer
  • Periampullary cancer

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Barreiro, C. J., Lillemoe, K. D., Koniaris, L. G., Sohn, T. A., Yeo, C. J., Coleman, J. A., Fishman, E. K., & Cameron, J. L. (2002). Diagnostic laparoscopy for periampullary and pancreatic cancer: What is the true benefit? Journal of Gastrointestinal Surgery, 6(1), 75-81. https://doi.org/10.1016/S1091-255X(01)00004-X