Diagnostic methodology and technology in molecular genetic pathology

Josephine Wu, Feiy Ye, Miao Cui, Robert Shibata, Ruliang Xu, Liang Cheng, David Y. Zhang

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The technology for molecular diagnosis has significantly advanced during the past decade that has led to revolutionary changes in molecular testing. This chapter describes common methodologies used in molecular diagnosis including sample collection and preparation, DNA detection and amplification, DNA sequencing, and proteomic methods. For each method, the principle, application, advantages, and limitations were discussed. However, for specific clinical application, please refer to other chapters contained in this book.

Original languageEnglish
Title of host publicationMolecular Genetic Pathology: Second Edition
PublisherSpringer New York
Pages211-300
Number of pages90
ISBN (Print)9781461448006, 1461447992, 9781461447993
DOIs
StatePublished - Mar 1 2014

Fingerprint

Molecular Pathology
Molecular Biology
Technology
DNA Sequence Analysis
Proteomics
DNA

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Wu, J., Ye, F., Cui, M., Shibata, R., Xu, R., Cheng, L., & Zhang, D. Y. (2014). Diagnostic methodology and technology in molecular genetic pathology. In Molecular Genetic Pathology: Second Edition (pp. 211-300). Springer New York. https://doi.org/10.1007/978-1-4614-4800-6-9

Diagnostic methodology and technology in molecular genetic pathology. / Wu, Josephine; Ye, Feiy; Cui, Miao; Shibata, Robert; Xu, Ruliang; Cheng, Liang; Zhang, David Y.

Molecular Genetic Pathology: Second Edition. Springer New York, 2014. p. 211-300.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wu, J, Ye, F, Cui, M, Shibata, R, Xu, R, Cheng, L & Zhang, DY 2014, Diagnostic methodology and technology in molecular genetic pathology. in Molecular Genetic Pathology: Second Edition. Springer New York, pp. 211-300. https://doi.org/10.1007/978-1-4614-4800-6-9
Wu J, Ye F, Cui M, Shibata R, Xu R, Cheng L et al. Diagnostic methodology and technology in molecular genetic pathology. In Molecular Genetic Pathology: Second Edition. Springer New York. 2014. p. 211-300 https://doi.org/10.1007/978-1-4614-4800-6-9
Wu, Josephine ; Ye, Feiy ; Cui, Miao ; Shibata, Robert ; Xu, Ruliang ; Cheng, Liang ; Zhang, David Y. / Diagnostic methodology and technology in molecular genetic pathology. Molecular Genetic Pathology: Second Edition. Springer New York, 2014. pp. 211-300
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