Diagnostic radiation and the risk of multiple myeloma (United States)

J. L. Hatcher, D. Baris, A. F. Olshan, P. D. Inskip, D. A. Savitz, G. M. Swanson, L. M. Pottern, R. S. Greenberg, A. G. Schwartz, J. B. Schoenberg, L. M. Brown

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objective: To evaluate the relationship between cumulative lifetime exposure to diagnostic radiation and the risk of multiple myeloma using data from a large, multi-center, population-based case-control study. Methods: Study subjects included a total of 540 cases with newly diagnosed multiple myeloma and 1998 frequency-matched population controls living in three areas of the United States (Georgia, Michigan, New Jersey). Information on exposure to diagnostic X-rays was obtained by personal interview. Results: No association was found between case-control status and the total number of reported diagnostic X-rays of any type (odds ratio (OR) for 20 or more compared to less than 5 X-rays = 0.9, 95% confidence interval (95% CI) = 0.7-1.2). There was no evidence of an excess risk of multiple myeloma among individuals who reported exposure to 10 or more diagnostic X-rays that impart a relatively high radiation dose to the bone marrow, as compared to individuals reporting no such exposures (OR 0.7, 95% CI 0.4-1.3). Conclusions: These data suggest that exposure to diagnostic X-rays has a negligible impact, if any, on risk of developing multiple myeloma.

Original languageEnglish (US)
Pages (from-to)755-761
Number of pages7
JournalCancer Causes and Control
Volume12
Issue number8
DOIs
StatePublished - 2001
Externally publishedYes

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Multiple Myeloma
Radiography
Radiation
Odds Ratio
Confidence Intervals
Population Control
Case-Control Studies
Bone Marrow
X-Rays
Interviews
Population

Keywords

  • Case-control studies
  • Ionizing radiation
  • Multiple myeloma
  • X-rays

ASJC Scopus subject areas

  • Oncology
  • Epidemiology
  • Cancer Research

Cite this

Hatcher, J. L., Baris, D., Olshan, A. F., Inskip, P. D., Savitz, D. A., Swanson, G. M., ... Brown, L. M. (2001). Diagnostic radiation and the risk of multiple myeloma (United States). Cancer Causes and Control, 12(8), 755-761. https://doi.org/10.1023/A:1011205908596

Diagnostic radiation and the risk of multiple myeloma (United States). / Hatcher, J. L.; Baris, D.; Olshan, A. F.; Inskip, P. D.; Savitz, D. A.; Swanson, G. M.; Pottern, L. M.; Greenberg, R. S.; Schwartz, A. G.; Schoenberg, J. B.; Brown, L. M.

In: Cancer Causes and Control, Vol. 12, No. 8, 2001, p. 755-761.

Research output: Contribution to journalArticle

Hatcher, JL, Baris, D, Olshan, AF, Inskip, PD, Savitz, DA, Swanson, GM, Pottern, LM, Greenberg, RS, Schwartz, AG, Schoenberg, JB & Brown, LM 2001, 'Diagnostic radiation and the risk of multiple myeloma (United States)', Cancer Causes and Control, vol. 12, no. 8, pp. 755-761. https://doi.org/10.1023/A:1011205908596
Hatcher JL, Baris D, Olshan AF, Inskip PD, Savitz DA, Swanson GM et al. Diagnostic radiation and the risk of multiple myeloma (United States). Cancer Causes and Control. 2001;12(8):755-761. https://doi.org/10.1023/A:1011205908596
Hatcher, J. L. ; Baris, D. ; Olshan, A. F. ; Inskip, P. D. ; Savitz, D. A. ; Swanson, G. M. ; Pottern, L. M. ; Greenberg, R. S. ; Schwartz, A. G. ; Schoenberg, J. B. ; Brown, L. M. / Diagnostic radiation and the risk of multiple myeloma (United States). In: Cancer Causes and Control. 2001 ; Vol. 12, No. 8. pp. 755-761.
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AU - Savitz, D. A.

AU - Swanson, G. M.

AU - Pottern, L. M.

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