Dietary factors and the risk of squamous cell esophageal cancer among black and white men in the United States

Linda Morris Brown, Christine A. Swanson, Gloria Gridley, G. Marie Swanson, Debra T. Silverman, Raymond S. Greenberg, Richard B. Hayes, Janet B. Schoenberg, Linda M. Pottern, Ann G. Schwartz, Jonathan M. Liff, Robert Hoover, Joseph F. Fraumeni

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Objectives: To investigate dietary factors for squamous cell esophageal cancer and whether these factors may contribute to the five-fold higher incidence of this cancer in the black versus white population of the United States. Methods: Data from a food frequency questionnaire were analyzed for 114 white men and 219 black men with squamous cell esophageal cancer, and 681 white and 557 black male controls from three areas of the United States who participated in a population-based case-control study of esophageal cancer. Results: Protective effects were associated with intake of raw fruits and vegetables (odds ratio for high versus low consumers = 0.3 in both white and black men) and use of vitamin supplements (especially vitamin C; odds ratio for high versus low consumers = 0.4 in both races), with the frequency of consumption of raw fruits and vegetables and vitamin supplements being greater for white than black controls. In addition, elevated risks were associated with high versus low intake of red meat (OR = 2.7 for blacks and 1.5 for whites) and processed meat (OR = 1.6 for blacks and 1.7 for whites), with the levels of consumption being greater for black than white controls. Conclusions: In the United States, these dietary factors may contribute in part to the much higher incidence of squamous cell esophageal cancer among black compared to white men.

Original languageEnglish (US)
Pages (from-to)467-474
Number of pages8
JournalCancer Causes and Control
Volume9
Issue number5
DOIs
StatePublished - 1998
Externally publishedYes

Fingerprint

Squamous Cell Neoplasms
Esophageal Neoplasms
Vitamins
Vegetables
Fruit
Odds Ratio
Incidence
hydroquinone
Meat
Population
Ascorbic Acid
Case-Control Studies
Food

Keywords

  • Case-control studies
  • Diet
  • Esophageal neoplasms
  • Raw fruit
  • Raw vegetables

ASJC Scopus subject areas

  • Oncology
  • Epidemiology
  • Cancer Research

Cite this

Brown, L. M., Swanson, C. A., Gridley, G., Swanson, G. M., Silverman, D. T., Greenberg, R. S., ... Fraumeni, J. F. (1998). Dietary factors and the risk of squamous cell esophageal cancer among black and white men in the United States. Cancer Causes and Control, 9(5), 467-474. https://doi.org/10.1023/A:1008861806923

Dietary factors and the risk of squamous cell esophageal cancer among black and white men in the United States. / Brown, Linda Morris; Swanson, Christine A.; Gridley, Gloria; Swanson, G. Marie; Silverman, Debra T.; Greenberg, Raymond S.; Hayes, Richard B.; Schoenberg, Janet B.; Pottern, Linda M.; Schwartz, Ann G.; Liff, Jonathan M.; Hoover, Robert; Fraumeni, Joseph F.

In: Cancer Causes and Control, Vol. 9, No. 5, 1998, p. 467-474.

Research output: Contribution to journalArticle

Brown, LM, Swanson, CA, Gridley, G, Swanson, GM, Silverman, DT, Greenberg, RS, Hayes, RB, Schoenberg, JB, Pottern, LM, Schwartz, AG, Liff, JM, Hoover, R & Fraumeni, JF 1998, 'Dietary factors and the risk of squamous cell esophageal cancer among black and white men in the United States', Cancer Causes and Control, vol. 9, no. 5, pp. 467-474. https://doi.org/10.1023/A:1008861806923
Brown, Linda Morris ; Swanson, Christine A. ; Gridley, Gloria ; Swanson, G. Marie ; Silverman, Debra T. ; Greenberg, Raymond S. ; Hayes, Richard B. ; Schoenberg, Janet B. ; Pottern, Linda M. ; Schwartz, Ann G. ; Liff, Jonathan M. ; Hoover, Robert ; Fraumeni, Joseph F. / Dietary factors and the risk of squamous cell esophageal cancer among black and white men in the United States. In: Cancer Causes and Control. 1998 ; Vol. 9, No. 5. pp. 467-474.
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