Differential diagnosis and diagnostic systems in schizophrenia

A. R. Doran, A. Breier, A. Roy

Research output: Contribution to journalReview article

12 Scopus citations


Diagnosis and prognosis are critical issues confronting psychiatry. In order to answer the fundamental questions concerning the origin and development of schizophrenia, we must first be clear about what it is. We must be able to separate the illness of schizophrenia from other disorders. We have attempted in this article to examine some of the illnesses that may resemble schizophrenia and make its discrimination difficult. We hope that by discussing these disorders and their similarities to schizophrenia the important issues and dilemmas have become clearer and more readily understood by the clinician. Future studies assessing the validity of diagnostic systems for schizophrenia may have to rely on features other than cross-sectional symptoms and longitudinal course. Such characteristics as pharmacologic responsivity and genetic transmisssion and the development of biologic markers may be the prospective cornerstones for validating the diagnosis of schizophrenia.

Original languageEnglish (US)
Pages (from-to)17-33
Number of pages17
JournalPsychiatric Clinics of North America
Issue number1
StatePublished - Jan 1 1986
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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