Difficulties in establishing routine amniocentesis for preterm labor evaluation

Jennifer J. McIntosh, Katherine McHugh, David M. Haas

Research output: Contribution to journalReview article

4 Scopus citations


After a recent practice change implementing amniocentesis into the evaluation of preterm labor (PTL) or preterm premature rupture of membranes (PPROM), actual performance of the procedure was tracked. Fifty-nine patients were admitted with these diagnoses. Twenty-three patients (39%) were offered amniocentesis and 36 patients (61%) were not offered amniocentesis as part of the clinical protocol. Seven (30%) patients of those offered an amniocentesis underwent the procedure. The predominant reasons for not performing an amniocentesis were patient refusal and provider discomfort. In conclusion, implementation of amniocentesis to evaluate for subclinical infection/ inflammation in the setting of PTL or PPROM proved difficult, as only 7 of 59 (11.9%) patients admitted with these diagnoses actually received an amniocentesis.

Original languageEnglish (US)
Pages (from-to)313-314
Number of pages2
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number3
StatePublished - Mar 1 2012


  • Amniocentesis
  • preterm labor
  • preterm premature rupture of membranes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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