Diffusion, perfusion, and histopathologic characteristics of desmoplastic infantile ganglioglioma

Chang Ho, Melissa Gener, Jose Bonnin, Stephen F. Kralik

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

We present a case series of a rare tumor, the desmoplastic infantile ganglioglioma (DIG) with MRI diffusion and perfusion imaging quantification as well as histopathologic characterization. Four cases with pathologically-proven DIG had diffusion weighted imaging (DWI) and two of the four had dynamic susceptibility contrast imaging. All four tumors demonstrate DWI findings compatible with low-grade pediatric tumors. For the two cases with perfusion imaging, a higher relative cerebral blood volume was associated with higher proliferation index on histopathology for one of the cases. Our results are discussed in conjunction with a literature review.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalJournal of Radiology Case Reports
Volume10
Issue number7
DOIs
StatePublished - Jul 1 2016

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Keywords

  • Desmoplastic infantile ganglioglioma
  • Diffusion
  • MRI
  • Pediatric brain tumors
  • Perfusion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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