Digitale fluoreszein-angiographie zur kontrolle des klinischen verlaufes unter therapie bei patienten mit zentralvenenverschluss und zystoidem makulaodem

Translated title of the contribution: Digital fluorescein angiography for therapeutic assessment of patients with central retinal vein occlusion and cystoid macular edema: Effect of a hemodilution and acetacolamide therapy

Oliver Arend, Andreas Remky, Uta Solbach, Alon Harris, Sebastian Wolf, Martin Reim

Research output: Contribution to journalArticle

5 Scopus citations


Background: Fluorescein angiography with a scanning laser ophthalmoscope allows the quantification of morphologic and dynamic changes in the retina. In two patients with central retinal vein occlusion we monitored the progression of the cystoid macular edema (CME) and changes of microcirculation with a follow up of 4 to 6 months. Materials and Methods: Two patients with central retinal vein occlusion and CME were examined by means of digital fluorescein angiography. Arteriovenous passage times and macular capillary blood velocities in combination with quantifications of the macular angioarchitecture and the extent of the CME were evaluated. Results: Hemodilution therapy improved retinal circulation, whereas macular circulation and the severity of the CME remained unchanged. With persisting CME oral acetazolamid therapy was initiated. Oral Acetazolamide led to resorption of the cystoid edema in tandem with improved macular circulation. The capillary density was altered but remained unchanged over time. Conclusions: By means of digital analysis of fluorescein angiograms a detailed monitoring of retinal and macular dynamics; macular morphology is possible. In these two cases CME improved after Acetazolamide and moreover retinal circulation returned to normal conditions.

Original languageGerman
Pages (from-to)163-170
Number of pages8
JournalKlinische Monatsblatter fur Augenheilkunde
Issue number2-3
StatePublished - Aug 1 1996



  • Acetacolamide
  • Central retinal vein occlusion
  • Digital image analysis
  • Fluorescein angiography

ASJC Scopus subject areas

  • Ophthalmology

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