Discharge patterns of chicken cochlear ganglion neurons following kanamycin-induced hair cell loss and regeneration

R. J. Salvi, S. S. Saunders, Eri Hashino, L. Chen

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Hair cells in the basal, high frequency region (>1100 Hz) of the chicken cochlea were destroyed with kanamycin (400 mg/kg/d × 10 d) and allowed to regenerate. Afterwards, single unit recordings were made from cochlear ganglion neurons at various times post-treatment. During the first few weeks post-treatment, only neurons with low characteristic frequencies (

Original languageEnglish (US)
Pages (from-to)351-369
Number of pages19
JournalJournal of Comparative Physiology A
Volume174
Issue number3
DOIs
StatePublished - Mar 1994
Externally publishedYes

Fingerprint

Kanamycin
Cochlea
Alopecia
kanamycin
hair
Ganglia
hairs
Regeneration
Chickens
regeneration
neurons
chickens
Neurons
cells
loss
post-treatment

Keywords

  • Cochlear ganglion neurons
  • Hair cell regeneration
  • Spontaneous activity
  • Threshold
  • Tuning curves

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neuroscience(all)
  • Physiology (medical)
  • Physiology
  • Animal Science and Zoology

Cite this

Discharge patterns of chicken cochlear ganglion neurons following kanamycin-induced hair cell loss and regeneration. / Salvi, R. J.; Saunders, S. S.; Hashino, Eri; Chen, L.

In: Journal of Comparative Physiology A, Vol. 174, No. 3, 03.1994, p. 351-369.

Research output: Contribution to journalArticle

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