Disease-specific outcomes assessment for diagnosis of colorectal neoplasia: From clinical trials to community practice

D. K. Rex, R. M. Ness

Research output: Contribution to journalReview article

2 Scopus citations


Maximizing the outcomes of any diagnostic or treatment strategy translated from clinical trials to community practice is a complex process. Certainly, this is true of screening and diagnostic strategies for colorectal cancer and polyps. First, clinicians must identify clinical trials with valid results. Second, questions should be posed regarding whether the population in community practice is similar to that of the study population in the clinical trial, whether the methodology of the trial is or can be reproduced in the community setting, and whether the individuals performing the strategies have comparable training and expertise to those in the clinical trial. Most importantly, monitoring the performance of the strategies in community practice identifies areas of strength and weakness and allows for decision making that optimizes patient outcomes.

Original languageEnglish (US)
Pages (from-to)697-704
Number of pages8
JournalGastrointestinal Endoscopy Clinics of North America
Issue number4
StatePublished - Oct 29 1999


ASJC Scopus subject areas

  • Gastroenterology

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