Disorders of proprioceptive responses in monkeys after cerebellar lesions: An analysis using the Denny-Brown Collection

Joel Vilensky, S. Wade Barnhart, Sid Gilman, Jennifer A. Cook, Robert J. Morecraft

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We used the Denny-Brown Research Collection to study in detail the reflex responses of monkeys after ablation of the anterior lobe, posterior lobe or the entire cerebellum. The Collection includes written, film and histological records, and photographs of the brain at autopsy. Large cerebellar ablations severely suppress proprioceptive responses, thereby significantly impairing the capacity to stand, walk, and hop. Cutaneous reflexes are also impaired, although more selectively, permitting expression of normally suppressed responses such as magnet reactions and tactile avoiding responses. Enhancement (release) of responses to truncal cutaneous stimulation, along with suppression of opposing proprioceptive responses, leads to postures of persistent flexion. Large cerebellar lesions also interfere with reflex responses mediated by visual and vestibular systems. More limited cerebellar ablations have similar, but less severe effects.

Original languageEnglish (US)
Pages (from-to)111-118
Number of pages8
JournalJournal of the Neurological Sciences
Volume163
Issue number2
DOIs
StatePublished - Mar 1 1999

Fingerprint

Somatosensory Disorders
Haplorhini
Reflex
Humulus
Skin
Magnets
Touch
Posture
Cerebellum
Autopsy
Brain
Research

Keywords

  • Cerebellum
  • Primates
  • Proprioception
  • Reflexes

ASJC Scopus subject areas

  • Aging
  • Clinical Neurology
  • Surgery
  • Developmental Neuroscience
  • Neurology
  • Neuroscience(all)

Cite this

Disorders of proprioceptive responses in monkeys after cerebellar lesions : An analysis using the Denny-Brown Collection. / Vilensky, Joel; Barnhart, S. Wade; Gilman, Sid; Cook, Jennifer A.; Morecraft, Robert J.

In: Journal of the Neurological Sciences, Vol. 163, No. 2, 01.03.1999, p. 111-118.

Research output: Contribution to journalArticle

Vilensky, Joel ; Barnhart, S. Wade ; Gilman, Sid ; Cook, Jennifer A. ; Morecraft, Robert J. / Disorders of proprioceptive responses in monkeys after cerebellar lesions : An analysis using the Denny-Brown Collection. In: Journal of the Neurological Sciences. 1999 ; Vol. 163, No. 2. pp. 111-118.
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