Disorders of sexual differentiation, gynecological, and anorectal abnormalities

Konrad Szymanski, Boaz Karmazyn, Richard C. Rink

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Evaluation and management of gynecological malformations, disorders of sexual differentiation (DSD), and anorectal malformation can be complex and often requires a multidisciplinary approach. Evaluation of these children includes a thorough physical examination, laboratory tests, imaging, and, occasionally, cystoscopy, vaginoscopy, hysteroscopy, and laparoscopy. A brief description of the embryology of the lower genitourinary tract is provided to understand the pathophysiology and classification of these malformations. Ultrasound should be the primary modality for the evaluation of most gynecologic and DSD pathologies. In more complex cases, a multimodal imaging approach is necessary to delineate the malformation and any associated anomalies. We describe the imaging approach in the diagnosis and management of interlabial masses (introital cysts, imperforate hymen, prolapsed ureterocele, and botryoides rhabdomyosarcoma tumor), internal gynecological abnormalities (vaginal agenesis, abnormalities of vertical fusion, and abnormalities of lateral fusion), DSD (complete androgen insensitivity syndrome, ovotesticular DSD, and urogenital sinus, including congenital adrenal hyperplasia), as well as anorectal anomalies (imperforate anus and cloacal malformation).

Original languageEnglish (US)
Title of host publicationPediatric and Adolescent Urologic Imaging
PublisherSpringer New York
Pages449-467
Number of pages19
ISBN (Print)9781461486541, 146148653X, 9781461486534
DOIs
StatePublished - Nov 1 2013

Fingerprint

Disorders of Sex Development
Imaging techniques
Fusion reactions
Laparoscopy
Multimodal Imaging
Ureterocele
Pathology
Imperforate Anus
Androgen-Insensitivity Syndrome
Congenital Adrenal Hyperplasia
Hysteroscopy
Androgens
Cystoscopy
Embryology
Rhabdomyosarcoma
Tumors
Ultrasonics
Physical Examination
Cysts
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Szymanski, K., Karmazyn, B., & Rink, R. C. (2013). Disorders of sexual differentiation, gynecological, and anorectal abnormalities. In Pediatric and Adolescent Urologic Imaging (pp. 449-467). Springer New York. https://doi.org/10.1007/978-1-4614-8654-1_21

Disorders of sexual differentiation, gynecological, and anorectal abnormalities. / Szymanski, Konrad; Karmazyn, Boaz; Rink, Richard C.

Pediatric and Adolescent Urologic Imaging. Springer New York, 2013. p. 449-467.

Research output: Chapter in Book/Report/Conference proceedingChapter

Szymanski, K, Karmazyn, B & Rink, RC 2013, Disorders of sexual differentiation, gynecological, and anorectal abnormalities. in Pediatric and Adolescent Urologic Imaging. Springer New York, pp. 449-467. https://doi.org/10.1007/978-1-4614-8654-1_21
Szymanski K, Karmazyn B, Rink RC. Disorders of sexual differentiation, gynecological, and anorectal abnormalities. In Pediatric and Adolescent Urologic Imaging. Springer New York. 2013. p. 449-467 https://doi.org/10.1007/978-1-4614-8654-1_21
Szymanski, Konrad ; Karmazyn, Boaz ; Rink, Richard C. / Disorders of sexual differentiation, gynecological, and anorectal abnormalities. Pediatric and Adolescent Urologic Imaging. Springer New York, 2013. pp. 449-467
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