Disparities in BRCA testing

when insurance coverage is not a barrier

Windy Olaya, Pamela Esquivel, Jan H. Wong, John W. Morgan, Adam Freeberg, Sharmila Roy-Chowdhury, Sharon S. Lum

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Background: Strategies to reduce the risk of developing breast and ovarian cancer in carriers of deleterious BRCA 1 and 2 mutations are readily available. However, many people who are at high risk of having these genetic mutations are reluctant to obtain the test. We sought to identify factors associated with choice of testing. Methods: We performed a retrospective cohort review of high-risk patients referred to a multidisciplinary breast health center for BRCA testing between January 2001 and March 2008. Demographic variables were compared by using logistic regression between those who completed genetic testing and those who did not. Results: A total of 213 patients were referred for BRCA testing. The mean age was 49.2 years (range, 16-84 y). Five patients were male. The majority of individuals (63.4%) were white, 15% were Hispanic, 6.6% were black, and 4.7% were Asian. Insurance coverage for testing was available in 91.1% of patients, of whom 49.2% had private insurance, 26.7% had managed care insurance, and 24.1% had government-sponsored insurance. A total of 111 patients (52.1%) underwent testing. On multivariate analysis, patients were significantly more likely to complete testing if they had a personal history of breast cancer (73.0% of tested patients) (P = .005) and had at least some college education (61.3%) (P = .03). There were no statistically significant differences in tested versus untested groups by age, race, language, family history, parity, marital status, religion, socioeconomic status, or insurance status. Of patients whose insurance plans offered coverage for genetic testing, 51.4% underwent testing and 48.6% did not (P = not significant [NS]). Of those who had no insurance coverage for testing, 41.2% underwent testing and 58.9% did not (P = NS). Conclusions: Our data show that half of those patients at risk for carrying a BRCA mutation do not undergo testing. Insurance coverage for genetic testing does not influence the decision to test. Developing counseling instruments that explain the benefits of testing to unaffected high-risk individuals or targeted to those with a high school level education may be a strategy to improve testing rates.

Original languageEnglish (US)
Pages (from-to)562-565
Number of pages4
JournalAmerican Journal of Surgery
Volume198
Issue number4
DOIs
StatePublished - Oct 2009
Externally publishedYes

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Insurance Coverage
Insurance
Genetic Testing
Mutation
Breast Neoplasms
Education
Marital Status
Religion
Managed Care Programs
Parity
Hispanic Americans
Social Class
Ovarian Neoplasms
Counseling
Breast
Language
Multivariate Analysis
Age Groups
Logistic Models
Demography

Keywords

  • BRCA mutation
  • Disparities
  • Genetic testing

ASJC Scopus subject areas

  • Surgery

Cite this

Olaya, W., Esquivel, P., Wong, J. H., Morgan, J. W., Freeberg, A., Roy-Chowdhury, S., & Lum, S. S. (2009). Disparities in BRCA testing: when insurance coverage is not a barrier. American Journal of Surgery, 198(4), 562-565. https://doi.org/10.1016/j.amjsurg.2009.07.003

Disparities in BRCA testing : when insurance coverage is not a barrier. / Olaya, Windy; Esquivel, Pamela; Wong, Jan H.; Morgan, John W.; Freeberg, Adam; Roy-Chowdhury, Sharmila; Lum, Sharon S.

In: American Journal of Surgery, Vol. 198, No. 4, 10.2009, p. 562-565.

Research output: Contribution to journalArticle

Olaya, W, Esquivel, P, Wong, JH, Morgan, JW, Freeberg, A, Roy-Chowdhury, S & Lum, SS 2009, 'Disparities in BRCA testing: when insurance coverage is not a barrier', American Journal of Surgery, vol. 198, no. 4, pp. 562-565. https://doi.org/10.1016/j.amjsurg.2009.07.003
Olaya W, Esquivel P, Wong JH, Morgan JW, Freeberg A, Roy-Chowdhury S et al. Disparities in BRCA testing: when insurance coverage is not a barrier. American Journal of Surgery. 2009 Oct;198(4):562-565. https://doi.org/10.1016/j.amjsurg.2009.07.003
Olaya, Windy ; Esquivel, Pamela ; Wong, Jan H. ; Morgan, John W. ; Freeberg, Adam ; Roy-Chowdhury, Sharmila ; Lum, Sharon S. / Disparities in BRCA testing : when insurance coverage is not a barrier. In: American Journal of Surgery. 2009 ; Vol. 198, No. 4. pp. 562-565.
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abstract = "Background: Strategies to reduce the risk of developing breast and ovarian cancer in carriers of deleterious BRCA 1 and 2 mutations are readily available. However, many people who are at high risk of having these genetic mutations are reluctant to obtain the test. We sought to identify factors associated with choice of testing. Methods: We performed a retrospective cohort review of high-risk patients referred to a multidisciplinary breast health center for BRCA testing between January 2001 and March 2008. Demographic variables were compared by using logistic regression between those who completed genetic testing and those who did not. Results: A total of 213 patients were referred for BRCA testing. The mean age was 49.2 years (range, 16-84 y). Five patients were male. The majority of individuals (63.4{\%}) were white, 15{\%} were Hispanic, 6.6{\%} were black, and 4.7{\%} were Asian. Insurance coverage for testing was available in 91.1{\%} of patients, of whom 49.2{\%} had private insurance, 26.7{\%} had managed care insurance, and 24.1{\%} had government-sponsored insurance. A total of 111 patients (52.1{\%}) underwent testing. On multivariate analysis, patients were significantly more likely to complete testing if they had a personal history of breast cancer (73.0{\%} of tested patients) (P = .005) and had at least some college education (61.3{\%}) (P = .03). There were no statistically significant differences in tested versus untested groups by age, race, language, family history, parity, marital status, religion, socioeconomic status, or insurance status. Of patients whose insurance plans offered coverage for genetic testing, 51.4{\%} underwent testing and 48.6{\%} did not (P = not significant [NS]). Of those who had no insurance coverage for testing, 41.2{\%} underwent testing and 58.9{\%} did not (P = NS). Conclusions: Our data show that half of those patients at risk for carrying a BRCA mutation do not undergo testing. Insurance coverage for genetic testing does not influence the decision to test. Developing counseling instruments that explain the benefits of testing to unaffected high-risk individuals or targeted to those with a high school level education may be a strategy to improve testing rates.",
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N2 - Background: Strategies to reduce the risk of developing breast and ovarian cancer in carriers of deleterious BRCA 1 and 2 mutations are readily available. However, many people who are at high risk of having these genetic mutations are reluctant to obtain the test. We sought to identify factors associated with choice of testing. Methods: We performed a retrospective cohort review of high-risk patients referred to a multidisciplinary breast health center for BRCA testing between January 2001 and March 2008. Demographic variables were compared by using logistic regression between those who completed genetic testing and those who did not. Results: A total of 213 patients were referred for BRCA testing. The mean age was 49.2 years (range, 16-84 y). Five patients were male. The majority of individuals (63.4%) were white, 15% were Hispanic, 6.6% were black, and 4.7% were Asian. Insurance coverage for testing was available in 91.1% of patients, of whom 49.2% had private insurance, 26.7% had managed care insurance, and 24.1% had government-sponsored insurance. A total of 111 patients (52.1%) underwent testing. On multivariate analysis, patients were significantly more likely to complete testing if they had a personal history of breast cancer (73.0% of tested patients) (P = .005) and had at least some college education (61.3%) (P = .03). There were no statistically significant differences in tested versus untested groups by age, race, language, family history, parity, marital status, religion, socioeconomic status, or insurance status. Of patients whose insurance plans offered coverage for genetic testing, 51.4% underwent testing and 48.6% did not (P = not significant [NS]). Of those who had no insurance coverage for testing, 41.2% underwent testing and 58.9% did not (P = NS). Conclusions: Our data show that half of those patients at risk for carrying a BRCA mutation do not undergo testing. Insurance coverage for genetic testing does not influence the decision to test. Developing counseling instruments that explain the benefits of testing to unaffected high-risk individuals or targeted to those with a high school level education may be a strategy to improve testing rates.

AB - Background: Strategies to reduce the risk of developing breast and ovarian cancer in carriers of deleterious BRCA 1 and 2 mutations are readily available. However, many people who are at high risk of having these genetic mutations are reluctant to obtain the test. We sought to identify factors associated with choice of testing. Methods: We performed a retrospective cohort review of high-risk patients referred to a multidisciplinary breast health center for BRCA testing between January 2001 and March 2008. Demographic variables were compared by using logistic regression between those who completed genetic testing and those who did not. Results: A total of 213 patients were referred for BRCA testing. The mean age was 49.2 years (range, 16-84 y). Five patients were male. The majority of individuals (63.4%) were white, 15% were Hispanic, 6.6% were black, and 4.7% were Asian. Insurance coverage for testing was available in 91.1% of patients, of whom 49.2% had private insurance, 26.7% had managed care insurance, and 24.1% had government-sponsored insurance. A total of 111 patients (52.1%) underwent testing. On multivariate analysis, patients were significantly more likely to complete testing if they had a personal history of breast cancer (73.0% of tested patients) (P = .005) and had at least some college education (61.3%) (P = .03). There were no statistically significant differences in tested versus untested groups by age, race, language, family history, parity, marital status, religion, socioeconomic status, or insurance status. Of patients whose insurance plans offered coverage for genetic testing, 51.4% underwent testing and 48.6% did not (P = not significant [NS]). Of those who had no insurance coverage for testing, 41.2% underwent testing and 58.9% did not (P = NS). Conclusions: Our data show that half of those patients at risk for carrying a BRCA mutation do not undergo testing. Insurance coverage for genetic testing does not influence the decision to test. Developing counseling instruments that explain the benefits of testing to unaffected high-risk individuals or targeted to those with a high school level education may be a strategy to improve testing rates.

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