DisProt: A database of protein disorder

Slobodan Vucetic, Zoran Obradovic, Vladimir Vacic, Predrag Radivojac, Kang Peng, Lilia M. Iakoucheva, Marc S. Cortese, J. David Lawson, Celeste J. Brown, Jason G. Sikes, Crystal D. Newton, A. Keith Dunker

Research output: Contribution to journalArticle

172 Scopus citations

Abstract

Summary: The Database of Protein Disorder (DisProt) is a curated database that provides structure and function information about proteins that lack a fixed three-dimensional (3D) structure under putatively native conditions, either in their entirety or in part. Starting from the central premise that intrinsic disorder is an important structural class of protein and in order to meet the increasing interest thereof, DisProt is aimed at becoming a central repository of disorder-related information. For each disordered protein, the database includes the name of the protein, various aliases, accession codes, amino acid sequence, location of the disordered region(s), and methods used for structural (disorder) characterization. If applicable, most entries also list the biological function(s) of each disordered region, how each region of disorder is used for function, as well as provide links to PubMed abstracts and major protein databases.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalBioinformatics
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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    Vucetic, S., Obradovic, Z., Vacic, V., Radivojac, P., Peng, K., Iakoucheva, L. M., Cortese, M. S., Lawson, J. D., Brown, C. J., Sikes, J. G., Newton, C. D., & Dunker, A. K. (2005). DisProt: A database of protein disorder. Bioinformatics, 21(1), 137-140. https://doi.org/10.1093/bioinformatics/bth476