Disseminated Aspergillosis in a Previously Immunocompetent Host: A Case Report

Joshua Smith, Aliya Noor, Chadi Hage

Research output: Contribution to journalArticle

Abstract

ABSTRACT: Aspergillus infection can manifest in a variety of ways ranging from allergic bronchopulmonary aspergillosis to disseminated aspergillosis. Invasive disease is typically seen in the immunocompromised population but may rarely affect immunocompetent hosts. We present a case of a 48-year-old previously healthy man initially presenting with septic shock and multiorgan system failure. After stabilization, he developed persistent fevers with worsening mental status. Imaging of the brain revealed multiple hemorrhages with impending brain herniation. Postmortem examination revealed purulent abscesses in multiple organs with culture and microscopic evaluation revealing Aspergillus fumigatus.

Original languageEnglish (US)
JournalInfectious Diseases in Clinical Practice
DOIs
StateAccepted/In press - Oct 28 2015

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Allergic Bronchopulmonary Aspergillosis
Aspergillus fumigatus
Aspergillosis
Organ Culture Techniques
Aspergillus
Septic Shock
Neuroimaging
Abscess
Autopsy
Fever
Hemorrhage
Brain
Infection
Population

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Disseminated Aspergillosis in a Previously Immunocompetent Host : A Case Report. / Smith, Joshua; Noor, Aliya; Hage, Chadi.

In: Infectious Diseases in Clinical Practice, 28.10.2015.

Research output: Contribution to journalArticle

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