Disseminated choroid plexus papillomas in adults: A case series and review of the literature

Marwah M. Abdulkader, Nassir H. Mansour, Jamie J. Van Gompel, Gregory A. Bosh, Edward Dropcho, Jose Bonnin, Aaron Cohen-Gadol

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Choroid plexus papillomas (CPPs) are uncommon, usually intraventricular, low-grade tumors, accounting for less than 1% of all intracranial neoplasms and 2-4% of brain tumors in children. Dissemination of CPPs to multiple levels of the neuraxis has been seldom observed. Thus far, only 26 adult patients have been reported in the English language literature. With some exceptions, disseminated CPPs have been observed in adults and involved multiple sites along the cerebrospinal fluid pathways. Occasionally, intraparenchymal extension has been documented, and secondary involvement of the suprasellar region has been reported in only five patients. Postoperative treatment of CPPs has not been standardized. Most recommended therapies have been extrapolated from a series of atypical papillomas or carcinomas of the choroid plexus in children. We herein report a series of three patients of disseminated choroid plexus papillomas providing additional insights into this relatively rare entity.

Original languageEnglish (US)
JournalJournal of Clinical Neuroscience
DOIs
StateAccepted/In press - Apr 6 2016

Keywords

  • Adults
  • Choroid plexus papilloma
  • Disseminated

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

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